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HIF3A association with adiposity: the story begins before birth.
Pan H, Lin X, Wu Y, Chen L, Teh AL, Soh SE, Lee YS, Tint MT, MacIsaac JL, Morin AM, Tan KH, Yap F, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Gluckman PD, Karnani N, Holbrook JD; GUSTO Study Group. Pan H, et al. Among authors: holbrook jd. Epigenomics. 2015;7(6):937-50. doi: 10.2217/epi.15.45. Epub 2015 May 26. Epigenomics. 2015. PMID: 26011824 Free PMC article.
The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes.
Teh AL, Pan H, Chen L, Ong ML, Dogra S, Wong J, MacIsaac JL, Mah SM, McEwen LM, Saw SM, Godfrey KM, Chong YS, Kwek K, Kwoh CK, Soh SE, Chong MF, Barton S, Karnani N, Cheong CY, Buschdorf JP, Stünkel W, Kobor MS, Meaney MJ, Gluckman PD, Holbrook JD. Teh AL, et al. Among authors: holbrook jd. Genome Res. 2014 Jul;24(7):1064-74. doi: 10.1101/gr.171439.113. Epub 2014 Apr 7. Genome Res. 2014. PMID: 24709820 Free PMC article.
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome.
Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group. Lin X, et al. Among authors: holbrook jd. BMC Med. 2017 Mar 7;15(1):50. doi: 10.1186/s12916-017-0800-1. BMC Med. 2017. PMID: 28264723 Free PMC article.
Neonatal amygdalae and hippocampi are influenced by genotype and prenatal environment, and reflected in the neonatal DNA methylome.
Ong ML, Tuan TA, Poh J, Teh AL, Chen L, Pan H, MacIsaac JL, Kobor MS, Chong YS, Kwek K, Saw SM, Godfrey KM, Gluckman PD, Fortier MV, Karnani N, Meaney MJ, Qiu A, Holbrook JD. Ong ML, et al. Among authors: holbrook jd. Genes Brain Behav. 2019 Sep;18(7):e12576. doi: 10.1111/gbb.12576. Epub 2019 May 15. Genes Brain Behav. 2019. PMID: 31020763 Free article.
Choice of surrogate tissue influences neonatal EWAS findings.
Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N. Lin X, et al. Among authors: holbrook jd. BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x. BMC Med. 2017. PMID: 29202839 Free PMC article.
Prospective associations of appetitive traits at 3 and 12 months of age with body mass index and weight gain in the first 2 years of life.
Quah PL, Chan YH, Aris IM, Pang WW, Toh JY, Tint MT, Broekman BF, Saw SM, Kwek K, Godfrey KM, Gluckman PD, Chong YS, Meaney MJ, Yap FK, van Dam RM, Lee YS, Chong MF; GUSTO Study Group. Quah PL, et al. BMC Pediatr. 2015 Oct 12;15:153. doi: 10.1186/s12887-015-0467-8. BMC Pediatr. 2015. PMID: 26459321 Free PMC article. Clinical Trial.
Low birth weight associates with hippocampal gene expression.
Buschdorf JP, Ong ML, Ong SX, MacIsaac JL, Chng K, Kobor MS, Meaney MJ, Holbrook JD. Buschdorf JP, et al. Among authors: holbrook jd. Neuroscience. 2016 Mar 24;318:190-205. doi: 10.1016/j.neuroscience.2016.01.013. Epub 2016 Jan 12. Neuroscience. 2016. PMID: 26791528
109 results