Holbrook C - Search Results

1

Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.

Zengel J, Wang YX, Seo JW, Ning K, Hamilton JN, Wu B, Raie M, Holbrook C, Su S, Clements DR, Pillay S, Puschnik AS, Winslow MM, Idoyaga J, Nagamine CM, Sun Y, Mahajan VB, Ferrara KW, Blau HM, Carette JE. Zengel J, et al. Among authors: holbrook c. Nat Methods. 2023 Jul;20(7):1070-1081. doi: 10.1038/s41592-023-01896-x. Epub 2023 Jun 8. Nat Methods. 2023. PMID: 37291262 Free PMC article.

2

Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments.

Madl CM, Flaig IA, Holbrook CA, Wang YX, Blau HM. Madl CM, et al. Biomaterials. 2021 Aug;275:120973. doi: 10.1016/j.biomaterials.2021.120973. Epub 2021 Jun 14. Biomaterials. 2021. PMID: 34224984 Free PMC article.

3

Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation.

Johansson CB, Youssef S, Koleckar K, Holbrook C, Doyonnas R, Corbel SY, Steinman L, Rossi FM, Blau HM. Johansson CB, et al. Among authors: holbrook c. Nat Cell Biol. 2008 May;10(5):575-83. doi: 10.1038/ncb1720. Epub 2008 Apr 20. Nat Cell Biol. 2008. PMID: 18425116 Free PMC article.

4

Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors.

Togninalli M, Ho ATV, Madl CM, Holbrook CA, Wang YX, Magnusson KEG, Kirillova A, Chang A, Blau HM. Togninalli M, et al. NPJ Regen Med. 2023 Jan 14;8(1):4. doi: 10.1038/s41536-023-00277-4. NPJ Regen Med. 2023. PMID: 36639373 Free PMC article.

5

Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength.

Ho ATV, Palla AR, Blake MR, Yucel ND, Wang YX, Magnusson KEG, Holbrook CA, Kraft PE, Delp SL, Blau HM. Ho ATV, et al. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6675-6684. doi: 10.1073/pnas.1705420114. Epub 2017 Jun 12. Proc Natl Acad Sci U S A. 2017. PMID: 28607093 Free PMC article.

6

An In Vitro Model for Identifying Cardiac Side Effects of Anesthetics.

Chang ACY, Chang ACH, Nicin L, Weber GJ, Holbrook C, Davies MF, Blau HM, Bertaccini EJ. Chang ACY, et al. Among authors: holbrook c. Anesth Analg. 2020 Jan;130(1):e1-e4. doi: 10.1213/ANE.0000000000003757. Anesth Analg. 2020. PMID: 30198930 Free PMC article.

7

Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.

Ramunas J, Yakubov E, Brady JJ, Corbel SY, Holbrook C, Brandt M, Stein J, Santiago JG, Cooke JP, Blau HM. Ramunas J, et al. Among authors: holbrook c. FASEB J. 2015 May;29(5):1930-9. doi: 10.1096/fj.14-259531. Epub 2015 Jan 22. FASEB J. 2015. PMID: 25614443 Free PMC article.

8

Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength.

Palla AR, Ravichandran M, Wang YX, Alexandrova L, Yang AV, Kraft P, Holbrook CA, Schürch CM, Ho ATV, Blau HM. Palla AR, et al. Among authors: holbrook ca. Science. 2021 Jan 29;371(6528):eabc8059. doi: 10.1126/science.abc8059. Epub 2020 Dec 10. Science. 2021. PMID: 33303683 Free PMC article.

9

Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration.

Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf KI, Frésard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM. Porpiglia E, et al. Cell Stem Cell. 2022 Dec 1;29(12):1653-1668.e8. doi: 10.1016/j.stem.2022.10.009. Epub 2022 Nov 15. Cell Stem Cell. 2022. PMID: 36384141 Free PMC article.

10

Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes.

Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, Childers MK, Denning C, Day JW, Wu JC, Pruitt BL, Blau HM. Chang ACY, et al. Among authors: holbrook c. Stem Cell Reports. 2021 Sep 14;16(9):2169-2181. doi: 10.1016/j.stemcr.2021.04.018. Epub 2021 May 20. Stem Cell Reports. 2021. PMID: 34019816 Free PMC article.

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