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Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity.
Dufva O, Koski J, Maliniemi P, Ianevski A, Klievink J, Leitner J, Pölönen P, Hohtari H, Saeed K, Hannunen T, Ellonen P, Steinberger P, Kankainen M, Aittokallio T, Keränen MAI, Korhonen M, Mustjoki S. Dufva O, et al. Among authors: hohtari h. Blood. 2020 Feb 27;135(9):597-609. doi: 10.1182/blood.2019002121. Blood. 2020. PMID: 31830245 Free PMC article.
Characterization of p190-Bcr-Abl chronic myeloid leukemia reveals specific signaling pathways and therapeutic targets.
Adnan-Awad S, Kim D, Hohtari H, Javarappa KK, Brandstoetter T, Mayer I, Potdar S, Heckman CA, Kytölä S, Porkka K, Doma E, Sexl V, Kankainen M, Mustjoki S. Adnan-Awad S, et al. Among authors: hohtari h. Leukemia. 2021 Jul;35(7):1964-1975. doi: 10.1038/s41375-020-01082-4. Epub 2020 Nov 9. Leukemia. 2021. PMID: 33168949 Free PMC article.
Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS.
Brück OE, Lallukka-Brück SE, Hohtari HR, Ianevski A, Ebeling FT, Kovanen PE, Kytölä SI, Aittokallio TA, Ramos PM, Porkka KV, Mustjoki SM. Brück OE, et al. Among authors: hohtari hr. Blood Cancer Discov. 2021 Mar 22;2(3):238-249. doi: 10.1158/2643-3230.BCD-20-0162. eCollection 2021 May. Blood Cancer Discov. 2021. PMID: 34661156 Free PMC article.
Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival.
Brück O, Dufva O, Hohtari H, Blom S, Turkki R, Ilander M, Kovanen P, Pallaud C, Ramos PM, Lähteenmäki H, Välimäki K, El Missiry M, Ribeiro A, Kallioniemi O, Porkka K, Pellinen T, Mustjoki S. Brück O, et al. Among authors: hohtari h. Blood Adv. 2020 Jan 28;4(2):274-286. doi: 10.1182/bloodadvances.2019000792. Blood Adv. 2020. PMID: 31968078 Free PMC article.
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[No authors listed] [No authors listed] PMID: 35015673
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[No authors listed] [No authors listed] PMID: 34233291
16 results