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CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels.
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JM, de Oliveira GC, Gomez LS, Hogan KA, Tarragó MG, Puranik AS, Agorrody G, Thompson KL, Dang K, Clarke S, Childs BG, Kanamori KS, Witte MA, Vidal P, Kirkland AL, De Cecco M, Chellappa K, McReynolds MR, Jankowski C, Tchkonia T, Kirkland JL, Sedivy JM, van Deursen JM, Baker DJ, van Schooten W, Rabinowitz JD, Baur JA, Chini EN. Chini CCS, et al. Among authors: hogan ka. Nat Metab. 2020 Nov;2(11):1284-1304. doi: 10.1038/s42255-020-00298-z. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199925 Free PMC article.
Implications of the NADase CD38 in COVID pathophysiology.
Zeidler JD, Kashyap S, Hogan KA, Chini EN. Zeidler JD, et al. Among authors: hogan ka. Physiol Rev. 2022 Jan 1;102(1):339-341. doi: 10.1152/physrev.00007.2021. Epub 2021 Sep 8. Physiol Rev. 2022. PMID: 34494892 Free PMC article. Review.
The CD38 glycohydrolase and the NAD sink: implications for pathological conditions.
Zeidler JD, Hogan KA, Agorrody G, Peclat TR, Kashyap S, Kanamori KS, Gomez LS, Mazdeh DZ, Warner GM, Thompson KL, Chini CCS, Chini EN. Zeidler JD, et al. Among authors: hogan ka. Am J Physiol Cell Physiol. 2022 Mar 1;322(3):C521-C545. doi: 10.1152/ajpcell.00451.2021. Epub 2022 Feb 9. Am J Physiol Cell Physiol. 2022. PMID: 35138178 Free PMC article. Review.
68 results