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The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.
Sigaud R, Rösch L, Gatzweiler C, Benzel J, von Soosten L, Peterziel H, Selt F, Najafi S, Ayhan S, Gerloff XF, Hofmann N, Büdenbender I, Schmitt L, Foerster KI, Burhenne J, Haefeli WE, Korshunov A, Sahm F, van Tilburg CM, Jones DTW, Pfister SM, Knoerzer D, Kreider BL, Sauter M, Pajtler KW, Zuckermann M, Oehme I, Witt O, Milde T. Sigaud R, et al. Among authors: hofmann n. Neuro Oncol. 2023 Mar 14;25(3):566-579. doi: 10.1093/neuonc/noac183. Neuro Oncol. 2023. PMID: 35882450 Free PMC article.
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma.
Gutschner T, Hämmerle M, Pazaitis N, Bley N, Fiskin E, Uckelmann H, Heim A, Groβ M, Hofmann N, Geffers R, Skawran B, Longerich T, Breuhahn K, Schirmacher P, Mühleck B, Hüttelmaier S, Diederichs S. Gutschner T, et al. Among authors: hofmann n. Hepatology. 2014 May;59(5):1900-11. doi: 10.1002/hep.26997. Epub 2014 Apr 1. Hepatology. 2014. PMID: 24395596
Comprehensive bio-imaging using myocardial perfusion reserve index during cardiac magnetic resonance imaging and high-sensitive troponin T for the prediction of outcomes in heart transplant recipients.
Hofmann NP, Steuer C, Voss A, Erbel C, Celik S, Doesch A, Ehlermann P, Giannitsis E, Buss SJ, Katus HA, Korosoglou G. Hofmann NP, et al. Am J Transplant. 2014 Nov;14(11):2607-16. doi: 10.1111/ajt.12924. Epub 2014 Oct 7. Am J Transplant. 2014. PMID: 25293510 Free article.
Quantitative analysis of left ventricular strain using cardiac computed tomography.
Buss SJ, Schulz F, Mereles D, Hosch W, Galuschky C, Schummers G, Stapf D, Hofmann N, Giannitsis E, Hardt SE, Kauczor HU, Katus HA, Korosoglou G. Buss SJ, et al. Among authors: hofmann n. Eur J Radiol. 2014 Mar;83(3):e123-30. doi: 10.1016/j.ejrad.2013.11.026. Epub 2013 Dec 7. Eur J Radiol. 2014. PMID: 24368011
362 results