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A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity.
Roehlen N, Saviano A, El Saghire H, Crouchet E, Nehme Z, Del Zompo F, Jühling F, Oudot MA, Durand SC, Duong FHT, Cherradi S, Gonzalez Motos V, Almeida N, Ponsolles C, Heydmann L, Ostyn T, Lallement A, Pessaux P, Felli E, Cavalli A, Sgrignani J, Thumann C, Koutsopoulos O, Fuchs BC, Hoshida Y, Hofmann M, Vyberg M, Viuff BM, Galsgaard ED, Elson G, Toso A, Meyer M, Iacone R, Schweighoffer T, Teixeira G, Moll S, De Vito C, Roskams T, Davidson I, Heide D, Heikenwälder M, Zeisel MB, Lupberger J, Mailly L, Schuster C, Baumert TF. Roehlen N, et al. Among authors: hofmann m. Sci Transl Med. 2022 Dec 21;14(676):eabj4221. doi: 10.1126/scitranslmed.abj4221. Epub 2022 Dec 21. Sci Transl Med. 2022. PMID: 36542691
Follicular T helper cells shape the HCV-specific CD4+ T cell repertoire after virus elimination.
Smits M, Zoldan K, Ishaque N, Gu Z, Jechow K, Wieland D, Conrad C, Eils R, Fauvelle C, Baumert TF, Emmerich F, Bengsch B, Neumann-Haefelin C, Hofmann M, Thimme R, Boettler T. Smits M, et al. Among authors: hofmann m. J Clin Invest. 2020 Feb 3;130(2):998-1009. doi: 10.1172/JCI129642. J Clin Invest. 2020. PMID: 31697649 Free PMC article. Clinical Trial.
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
Kotsiliti E, Leone V, Schuehle S, Govaere O, Li H, Wolf MJ, Horvatic H, Bierwirth S, Hundertmark J, Inverso D, Zizmare L, Sarusi-Portuguez A, Gupta R, O'Connor T, Giannou AD, Shiri AM, Schlesinger Y, Beccaria MG, Rennert C, Pfister D, Öllinger R, Gadjalova I, Ramadori P, Rahbari M, Rahbari N, Healy ME, Fernández-Vaquero M, Yahoo N, Janzen J, Singh I, Fan C, Liu X, Rau M, Feuchtenberger M, Schwaneck E, Wallace SJ, Cockell S, Wilson-Kanamori J, Ramachandran P, Kho C, Kendall TJ, Leblond AL, Keppler SJ, Bielecki P, Steiger K, Hofmann M, Rippe K, Zitzelsberger H, Weber A, Malek N, Luedde T, Vucur M, Augustin HG, Flavell R, Parnas O, Rad R, Pabst O, Henderson NC, Huber S, Macpherson A, Knolle P, Claassen M, Geier A, Trautwein C, Unger K, Elinav E, Waisman A, Abdullah Z, Haller D, Tacke F, Anstee QM, Heikenwalder M. Kotsiliti E, et al. Among authors: hofmann m. J Hepatol. 2023 Aug;79(2):296-313. doi: 10.1016/j.jhep.2023.04.037. Epub 2023 May 22. J Hepatol. 2023. PMID: 37224925 Free PMC article.
Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands.
Raute K, Strietz J, Parigiani MA, Andrieux G, Thomas OS, Kistner KM, Zintchenko M, Aichele P, Hofmann M, Zhou H, Weber W, Boerries M, Swamy M, Maurer J, Minguet S. Raute K, et al. Among authors: hofmann m. Cancer Immunol Res. 2023 Jun 2;11(6):810-829. doi: 10.1158/2326-6066.CIR-22-0296. Cancer Immunol Res. 2023. PMID: 37139603 Free PMC article.
Ustekinumab Inhibits T Follicular Helper Cell Differentiation in Patients With Crohn's Disease.
Globig AM, Sommer NP, Wild K, Schardey J, Zoldan K, Thomann AK, Schulte LA, Schreiner R, Reindl W, Klaus J, Schempp CM, Hofmann M, Thimme R, Boettler T, Hasselblatt P. Globig AM, et al. Among authors: hofmann m. Cell Mol Gastroenterol Hepatol. 2021;11(1):1-12. doi: 10.1016/j.jcmgh.2020.07.005. Epub 2020 Jul 15. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32679193 Free PMC article.
CD8+ T Cell Responses during HCV Infection and HCC.
Hofmann M, Tauber C, Hensel N, Thimme R. Hofmann M, et al. J Clin Med. 2021 Mar 2;10(5):991. doi: 10.3390/jcm10050991. J Clin Med. 2021. PMID: 33801203 Free PMC article. Review.
1,622 results