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The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.
Gaengel K, Niaudet C, Hagikura K, Laviña B, Muhl L, Hofmann JJ, Ebarasi L, Nyström S, Rymo S, Chen LL, Pang MF, Jin Y, Raschperger E, Roswall P, Schulte D, Benedito R, Larsson J, Hellström M, Fuxe J, Uhlén P, Adams R, Jakobsson L, Majumdar A, Vestweber D, Uv A, Betsholtz C. Gaengel K, et al. Among authors: hofmann jj. Dev Cell. 2012 Sep 11;23(3):587-99. doi: 10.1016/j.devcel.2012.08.005. Dev Cell. 2012. PMID: 22975327 Free article.
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium.
Niaudet C, Hofmann JJ, Mäe MA, Jung B, Gaengel K, Vanlandewijck M, Ekvärn E, Salvado MD, Mehlem A, Al Sayegh S, He L, Lebouvier T, Castro-Freire M, Katayama K, Hultenby K, Moessinger C, Tannenberg P, Cunha S, Pietras K, Laviña B, Hong J, Berg T, Betsholtz C. Niaudet C, et al. Among authors: hofmann jj. PLoS One. 2015 Sep 22;10(9):e0137949. doi: 10.1371/journal.pone.0137949. eCollection 2015. PLoS One. 2015. PMID: 26394398 Free PMC article.
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalén M, Gerhardt H, Betsholtz C. Hellström M, et al. Among authors: hofmann jj. Nature. 2007 Feb 15;445(7129):776-80. doi: 10.1038/nature05571. Epub 2007 Jan 28. Nature. 2007. PMID: 17259973
Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis.
Shang MM, Talukdar HA, Hofmann JJ, Niaudet C, Asl HF, Jain RK, Rossignoli A, Cedergren C, Silveira A, Gigante B, Leander K, de Faire U, Hamsten A, Ruusalepp A, Melander O, Ivert T, Michoel T, Schadt EE, Betsholtz C, Skogsberg J, Björkegren JL. Shang MM, et al. Among authors: hofmann jj. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2068-77. doi: 10.1161/ATVBAHA.113.302709. Epub 2014 Jun 12. Arterioscler Thromb Vasc Biol. 2014. PMID: 24925974
Fate tracing reveals the endothelial origin of hematopoietic stem cells.
Zovein AC, Hofmann JJ, Lynch M, French WJ, Turlo KA, Yang Y, Becker MS, Zanetta L, Dejana E, Gasson JC, Tallquist MD, Iruela-Arispe ML. Zovein AC, et al. Among authors: hofmann jj. Cell Stem Cell. 2008 Dec 4;3(6):625-36. doi: 10.1016/j.stem.2008.09.018. Cell Stem Cell. 2008. PMID: 19041779 Free PMC article.
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