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Saraf-dependent activation of mTORC1 regulates cardiac growth.
Sanlialp A, Schumacher D, Kiper L, Varma E, Riechert E, Ho TC, Hofmann C, Kmietczyk V, Zimmermann F, Dlugosz S, Wirth A, Gorska AA, Burghaus J, Camacho Londoño JE, Katus HA, Doroudgar S, Freichel M, Völkers M. Sanlialp A, et al. Among authors: hofmann c. J Mol Cell Cardiol. 2020 Apr;141:30-42. doi: 10.1016/j.yjmcc.2020.03.004. Epub 2020 Mar 13. J Mol Cell Cardiol. 2020. PMID: 32173353
ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.
Blackwood EA, Hofmann C, Santo Domingo M, Bilal AS, Sarakki A, Stauffer W, Arrieta A, Thuerauf DJ, Kolkhorst FW, Müller OJ, Jakobi T, Dieterich C, Katus HA, Doroudgar S, Glembotski CC. Blackwood EA, et al. Among authors: hofmann c. Circ Res. 2019 Jan 4;124(1):79-93. doi: 10.1161/CIRCRESAHA.118.313854. Circ Res. 2019. PMID: 30582446 Free PMC article.
m6A-mRNA methylation regulates cardiac gene expression and cellular growth.
Kmietczyk V, Riechert E, Kalinski L, Boileau E, Malovrh E, Malone B, Gorska A, Hofmann C, Varma E, Jürgensen L, Kamuf-Schenk V, Altmüller J, Tappu R, Busch M, Most P, Katus HA, Dieterich C, Völkers M. Kmietczyk V, et al. Among authors: hofmann c. Life Sci Alliance. 2019 Apr 9;2(2):e201800233. doi: 10.26508/lsa.201800233. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30967445 Free PMC article.
Protein Misfolding in Cardiac Disease.
Hofmann C, Katus HA, Doroudgar S. Hofmann C, et al. Circulation. 2019 Apr 30;139(18):2085-2088. doi: 10.1161/CIRCULATIONAHA.118.037417. Circulation. 2019. PMID: 31034286 Review. No abstract available.
Monitoring Cell-Type-Specific Gene Expression Using Ribosome Profiling In Vivo During Cardiac Hemodynamic Stress.
Doroudgar S, Hofmann C, Boileau E, Malone B, Riechert E, Gorska AA, Jakobi T, Sandmann C, Jürgensen L, Kmietczyk V, Malovrh E, Burghaus J, Rettel M, Stein F, Younesi F, Friedrich UA, Mauz V, Backs J, Kramer G, Katus HA, Dieterich C, Völkers M. Doroudgar S, et al. Among authors: hofmann c. Circ Res. 2019 Aug 2;125(4):431-448. doi: 10.1161/CIRCRESAHA.119.314817. Epub 2019 Jul 9. Circ Res. 2019. PMID: 31284834 Free PMC article.
Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes.
Riechert E, Kmietczyk V, Stein F, Schwarzl T, Sekaran T, Jürgensen L, Kamuf-Schenk V, Varma E, Hofmann C, Rettel M, Gür K, Ölschläger J, Kühl F, Martin J, Ramirez-Pedraza M, Fernandez M, Doroudgar S, Méndez R, Katus HA, Hentze MW, Völkers M. Riechert E, et al. Among authors: hofmann c. Cell Rep. 2021 May 11;35(6):109100. doi: 10.1016/j.celrep.2021.109100. Cell Rep. 2021. PMID: 33979607 Free article.
Muscle-specific Cand2 is translationally upregulated by mTORC1 and promotes adverse cardiac remodeling.
Górska AA, Sandmann C, Riechert E, Hofmann C, Malovrh E, Varma E, Kmietczyk V, Ölschläger J, Jürgensen L, Kamuf-Schenk V, Stroh C, Furkel J, Konstandin MH, Sticht C, Boileau E, Dieterich C, Frey N, Katus HA, Doroudgar S, Völkers M. Górska AA, et al. Among authors: hofmann c. EMBO Rep. 2021 Dec 6;22(12):e52170. doi: 10.15252/embr.202052170. Epub 2021 Oct 4. EMBO Rep. 2021. PMID: 34605609 Free PMC article.
646 results