Hoflack J - Search Results

1

Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors.

Ma J, Ren J, Thorikay M, van Dinther M, Sanchez-Duffhues G, Caradec J, Benderitter P, Hoflack J, Ten Dijke P. Ma J, et al. Among authors: hoflack j. Cancers (Basel). 2021 Jun 12;13(12):2951. doi: 10.3390/cancers13122951. Cancers (Basel). 2021. PMID: 34204675 Free PMC article.

2

Development of small macrocyclic kinase inhibitors.

Ma J, Sanchez-Duffhues G, Caradec J, Benderitter P, Hoflack J, Dijke PT. Ma J, et al. Among authors: hoflack j. Future Med Chem. 2022 Mar;14(6):389-391. doi: 10.4155/fmc-2021-0342. Epub 2022 Jan 14. Future Med Chem. 2022. PMID: 35029506 Free article. No abstract available.

3

Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells.

Sánchez-Duffhues G, Williams E, Benderitter P, Orlova V, van Wijhe M, Garcia de Vinuesa A, Kerr G, Caradec J, Lodder K, de Boer HC, Goumans MJ, Eekhoff EMW, Morales-Piga A, Bachiller-Corral J, Koolwijk P, Bullock AN, Hoflack J, Ten Dijke P. Sánchez-Duffhues G, et al. Among authors: hoflack j. JBMR Plus. 2019 Oct 7;3(11):e10230. doi: 10.1002/jbm4.10230. eCollection 2019 Nov. JBMR Plus. 2019. PMID: 31768489 Free PMC article.

4

In vivo inhibition of RIPK2 kinase alleviates inflammatory disease.

Tigno-Aranjuez JT, Benderitter P, Rombouts F, Deroose F, Bai X, Mattioli B, Cominelli F, Pizarro TT, Hoflack J, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: hoflack j. J Biol Chem. 2014 Oct 24;289(43):29651-64. doi: 10.1074/jbc.M114.591388. Epub 2014 Sep 11. J Biol Chem. 2014. PMID: 25213858 Free PMC article.

5

The binding site of neuropeptide vasopressin V1a receptor. Evidence for a major localization within transmembrane regions.

Mouillac B, Chini B, Balestre MN, Elands J, Trumpp-Kallmeyer S, Hoflack J, Hibert M, Jard S, Barberis C. Mouillac B, et al. Among authors: hoflack j. J Biol Chem. 1995 Oct 27;270(43):25771-7. doi: 10.1074/jbc.270.43.25771. J Biol Chem. 1995. PMID: 7592759 Free article.

6

Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.

Chini B, Mouillac B, Ala Y, Balestre MN, Trumpp-Kallmeyer S, Hoflack J, Elands J, Hibert M, Manning M, Jard S, et al. Chini B, et al. Among authors: hoflack j. EMBO J. 1995 May 15;14(10):2176-82. doi: 10.1002/j.1460-2075.1995.tb07211.x. EMBO J. 1995. PMID: 7774575 Free PMC article.

7

Identification of agonist binding sites of vasopressin and oxytocin receptors.

Mouillac B, Chini B, Balestre MN, Jard S, Barberis C, Manning M, Tribollet E, Trumpp-Kallmeyer S, Hoflack J, Elands J, et al. Mouillac B, et al. Among authors: hoflack j. Adv Exp Med Biol. 1995;395:301-10. Adv Exp Med Biol. 1995. PMID: 8713980

8

Molecular basis for agonist selectivity in the vasopressin/oxytocin receptor family.

Chini B, Mouillac B, Ala Y, Balestre MN, Cotte N, Trumpp-Kallmeyer S, Hoflack J, Elands J, Hibert M, Manning M, et al. Chini B, et al. Among authors: hoflack j. Adv Exp Med Biol. 1995;395:321-8. Adv Exp Med Biol. 1995. PMID: 8713982

9

Identification of a single residue responsible for agonist selectivity in the oxytocin-vasopressin receptors.

Chini B, Mouillac B, Ala Y, Balestre MN, Trumpp-Kallmeyer S, Hoflack J, Elands J, Hibert M, Manning M, Jard S, Barberis C. Chini B, et al. Among authors: hoflack j. Ann N Y Acad Sci. 1997 May 30;812:218-21. doi: 10.1111/j.1749-6632.1997.tb48181.x. Ann N Y Acad Sci. 1997. PMID: 9186749 No abstract available.

10

Modelling of the binding site of the human m1 muscarinic receptor: experimental validation and refinement.

Bourdon H, Trumpp-Kallmeyer S, Schreuder H, Hoflack J, Hibert M, Wermuth CG. Bourdon H, et al. Among authors: hoflack j. J Comput Aided Mol Des. 1997 Jul;11(4):317-32. doi: 10.1023/a:1007963327888. J Comput Aided Mol Des. 1997. PMID: 9334899

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