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Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution.
Elsner F, Hoffmann M, Fahrioglu-Yamaci R, Czyz Z, Feliciello G, Mederer T, Polzer B, Treitschke S, Rümmele P, Weber F, Wiesinger H, Robold T, Sziklavari Z, Sienel W, Hofmann HS, Klein CA. Elsner F, et al. Among authors: hoffmann m. J Pathol. 2022 Nov;258(3):250-263. doi: 10.1002/path.5996. Epub 2022 Sep 23. J Pathol. 2022. PMID: 36148685
Reliable single cell array CGH for clinical samples.
Czyż ZT, Hoffmann M, Schlimok G, Polzer B, Klein CA. Czyż ZT, et al. Among authors: hoffmann m. PLoS One. 2014 Jan 21;9(1):e85907. doi: 10.1371/journal.pone.0085907. eCollection 2014. PLoS One. 2014. PMID: 24465780 Free PMC article.
Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia.
Ebinger S, Özdemir EZ, Ziegenhain C, Tiedt S, Castro Alves C, Grunert M, Dworzak M, Lutz C, Turati VA, Enver T, Horny HP, Sotlar K, Parekh S, Spiekermann K, Hiddemann W, Schepers A, Polzer B, Kirsch S, Hoffmann M, Knapp B, Hasenauer J, Pfeifer H, Panzer-Grümayer R, Enard W, Gires O, Jeremias I. Ebinger S, et al. Among authors: hoffmann m. Cancer Cell. 2016 Dec 12;30(6):849-862. doi: 10.1016/j.ccell.2016.11.002. Epub 2016 Dec 1. Cancer Cell. 2016. PMID: 27916615 Free PMC article.
Early dissemination seeds metastasis in breast cancer.
Hosseini H, Obradović MMS, Hoffmann M, Harper KL, Sosa MS, Werner-Klein M, Nanduri LK, Werno C, Ehrl C, Maneck M, Patwary N, Haunschild G, Gužvić M, Reimelt C, Grauvogl M, Eichner N, Weber F, Hartkopf AD, Taran FA, Brucker SY, Fehm T, Rack B, Buchholz S, Spang R, Meister G, Aguirre-Ghiso JA, Klein CA. Hosseini H, et al. Among authors: hoffmann m. Nature. 2016 Dec 22;540(7634):552-558. doi: 10.1038/nature20785. Epub 2016 Dec 14. Nature. 2016. PMID: 27974799 Free PMC article.
Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma.
Schumacher S, Bartenhagen C, Hoffmann M, Will D, Fischer JC, Baldus SE, Vay C, Fluegen G, Dizdar L, Vallböhmer D, Klein CA, Knoefel WT, Stoecklein NH, Möhlendick B. Schumacher S, et al. Among authors: hoffmann m. Br J Cancer. 2017 Aug 22;117(5):725-733. doi: 10.1038/bjc.2017.233. Epub 2017 Jul 20. Br J Cancer. 2017. PMID: 28728164 Free PMC article.
Diagnostic pathology of early systemic cancer: ERBB2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer.
Hoffmann M, Pasch S, Schamberger T, Maneck M, Möhlendick B, Schumacher S, Brockhoff G, Knoefel WT, Izbicki J, Polzer B, Stoecklein NH, Klein CA. Hoffmann M, et al. Int J Cancer. 2018 Feb 15;142(4):833-843. doi: 10.1002/ijc.31108. Epub 2017 Nov 30. Int J Cancer. 2018. PMID: 29044505 Free article.
Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma.
Werner-Klein M, Scheitler S, Hoffmann M, Hodak I, Dietz K, Lehnert P, Naimer V, Polzer B, Treitschke S, Werno C, Markiewicz A, Weidele K, Czyz Z, Hohenleutner U, Hafner C, Haferkamp S, Berneburg M, Rümmele P, Ulmer A, Klein CA. Werner-Klein M, et al. Among authors: hoffmann m. Nat Commun. 2018 Feb 9;9(1):595. doi: 10.1038/s41467-017-02674-y. Nat Commun. 2018. PMID: 29426936 Free PMC article.
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency.
Werner-Klein M, Grujovic A, Irlbeck C, Obradović M, Hoffmann M, Koerkel-Qu H, Lu X, Treitschke S, Köstler C, Botteron C, Weidele K, Werno C, Polzer B, Kirsch S, Gužvić M, Warfsmann J, Honarnejad K, Czyz Z, Feliciello G, Blochberger I, Grunewald S, Schneider E, Haunschild G, Patwary N, Guetter S, Huber S, Rack B, Harbeck N, Buchholz S, Rümmele P, Heine N, Rose-John S, Klein CA. Werner-Klein M, et al. Among authors: hoffmann m. Nat Commun. 2020 Oct 5;11(1):4977. doi: 10.1038/s41467-020-18701-4. Nat Commun. 2020. PMID: 33020483 Free PMC article.
3,521 results