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GFP-complementation assay to detect functional CPP and protein delivery into living cells.
Milech N, Longville BA, Cunningham PT, Scobie MN, Bogdawa HM, Winslow S, Anastasas M, Connor T, Ong F, Stone SR, Kerfoot M, Heinrich T, Kroeger KM, Tan YF, Hoffmann K, Thomas WR, Watt PM, Hopkins RM. Milech N, et al. Among authors: hoffmann k. Sci Rep. 2015 Dec 16;5:18329. doi: 10.1038/srep18329. Sci Rep. 2015. PMID: 26671759 Free PMC article.
A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery.
Hoffmann K, Milech N, Juraja SM, Cunningham PT, Stone SR, Francis RW, Anastasas M, Hall CM, Heinrich T, Bogdawa HM, Winslow S, Scobie MN, Dewhurst RE, Florez L, Ong F, Kerfoot M, Champain D, Adams AM, Fletcher S, Viola HM, Hool LC, Connor T, Longville BAC, Tan YF, Kroeger K, Morath V, Weiss GA, Skerra A, Hopkins RM, Watt PM. Hoffmann K, et al. Sci Rep. 2018 Aug 22;8(1):12538. doi: 10.1038/s41598-018-30790-2. Sci Rep. 2018. PMID: 30135446 Free PMC article.
Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers.
Wang E, Sorolla A, Cunningham PT, Bogdawa HM, Beck S, Golden E, Dewhurst RE, Florez L, Cruickshank MN, Hoffmann K, Hopkins RM, Kim J, Woo AJ, Watt PM, Blancafort P. Wang E, et al. Among authors: hoffmann k. Oncogene. 2019 Jan;38(1):140-150. doi: 10.1038/s41388-018-0421-y. Epub 2018 Aug 3. Oncogene. 2019. PMID: 30076412 Free PMC article.
Poly-arginine and arginine-rich peptides are neuroprotective in stroke models.
Meloni BP, Brookes LM, Clark VW, Cross JL, Edwards AB, Anderton RS, Hopkins RM, Hoffmann K, Knuckey NW. Meloni BP, et al. Among authors: hoffmann k. J Cereb Blood Flow Metab. 2015 Jun;35(6):993-1004. doi: 10.1038/jcbfm.2015.11. Epub 2015 Feb 11. J Cereb Blood Flow Metab. 2015. PMID: 25669902 Free PMC article.
Questing for homoleptic mononuclear manganese complexes with monodentate O-donor ligands.
Pérez-Bitrián A, Munárriz J, Krause KB, Schlögl J, Hoffmann KF, Sturm JS, Hadi AN, Teutloff C, Wiesner A, Limberg C, Riedel S. Pérez-Bitrián A, et al. Among authors: hoffmann kf. Chem Sci. 2024 Mar 5;15(15):5564-5572. doi: 10.1039/d4sc00543k. eCollection 2024 Apr 17. Chem Sci. 2024. PMID: 38638238 Free PMC article.
Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells.
Albanese M, Chen HR, Gapp M, Muenchhoff M, Yang HH, Peterhoff D, Hoffmann K, Xiao Q, Ruhle A, Ambiel I, Schneider S, Mejías-Pérez E, Stern M, Wratil PR, Hofmann K, Amann L, Jocham L, Fuchs T, Ulivi AF, Besson-Girard S, Weidlich S, Schneider J, Spinner CD, Sutter K, Dittmer U, Humpe A, Baumeister P, Wieser A, Rothenfusser S, Bogner J, Roider J, Knolle P, Hengel H, Wagner R, Laketa V, Fackler OT, Keppler OT. Albanese M, et al. Among authors: hoffmann k. Cell Rep Med. 2024 Apr 16;5(4):101483. doi: 10.1016/j.xcrm.2024.101483. Epub 2024 Apr 4. Cell Rep Med. 2024. PMID: 38579727 Free PMC article.
2,562 results