Hoffman RM - Search Results

1

Exploiting methionine restriction for cancer treatment.

Chaturvedi S, Hoffman RM, Bertino JR. Chaturvedi S, et al. Among authors: hoffman rm. Biochem Pharmacol. 2018 Aug;154:170-173. doi: 10.1016/j.bcp.2018.05.003. Epub 2018 May 4. Biochem Pharmacol. 2018. PMID: 29733806 Review.

2

Expression of the biochemical defect of methionine dependence in fresh patient tumors in primary histoculture.

Guo HY, Herrera H, Groce A, Hoffman RM. Guo HY, et al. Among authors: hoffman rm. Cancer Res. 1993 Jun 1;53(11):2479-83. Cancer Res. 1993. PMID: 8495409

3

Serum methionine depletion without side effects by methioninase in metastatic breast cancer patients.

Tan Y, Zavala J Sr, Xu M, Zavala J Jr, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1996 Nov-Dec;16(6C):3937-42. Anticancer Res. 1996. PMID: 9042316 Clinical Trial.

4

Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey.

Hoffman RM. Hoffman RM. Expert Opin Biol Ther. 2015 Jan;15(1):21-31. doi: 10.1517/14712598.2015.963050. Epub 2014 Dec 2. Expert Opin Biol Ther. 2015. PMID: 25439528 Review.

5

Methionine Dependency Determination of Human Patient Tumors in Gelfoam^® Histoculture.

Hoffman RM. Hoffman RM. Methods Mol Biol. 2018;1760:125-131. doi: 10.1007/978-1-4939-7745-1_13. Methods Mol Biol. 2018. PMID: 29572800

6

Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer.

Kawaguchi K, Miyake K, Han Q, Li S, Tan Y, Igarashi K, Lwin TM, Higuchi T, Kiyuna T, Miyake M, Oshiro H, Bouvet M, Unno M, Hoffman RM. Kawaguchi K, et al. Among authors: hoffman rm. Cell Cycle. 2018;17(7):868-873. doi: 10.1080/15384101.2018.1445907. Epub 2018 May 21. Cell Cycle. 2018. PMID: 29623758 Free PMC article.

7

Altered Methionine Metabolism in Cancer Cells.

Hoffman RM, Stern PH, Coalson DW, Douglas Wallace C, Erbe RW. Hoffman RM, et al. Methods Mol Biol. 2019;1866:13-26. doi: 10.1007/978-1-4939-8796-2_2. Methods Mol Biol. 2019. PMID: 30725404

8

Linkage of Methionine Dependence and Other Features of Malignancy.

Hoffman RM, Erbe RW. Hoffman RM, et al. Methods Mol Biol. 2019;1866:27-36. doi: 10.1007/978-1-4939-8796-2_3. Methods Mol Biol. 2019. PMID: 30725405

9

Tumor-Specific S/G₂-Phase Cell Cycle Arrest of Cancer Cells by Methionine Restriction.

Hoffman RM, Yano S. Hoffman RM, et al. Methods Mol Biol. 2019;1866:49-60. doi: 10.1007/978-1-4939-8796-2_5. Methods Mol Biol. 2019. PMID: 30725407

10

Efficacy of Methionine-Restricted Diets on Cancers In Vivo.

Hoffman RM, Hoshiya Y, Guo W. Hoffman RM, et al. Methods Mol Biol. 2019;1866:75-81. doi: 10.1007/978-1-4939-8796-2_7. Methods Mol Biol. 2019. PMID: 30725409

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