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Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models.
Costa-Machado LF, Garcia-Dominguez E, McIntyre RL, Lopez-Aceituno JL, Ballesteros-Gonzalez Á, Tapia-Gonzalez A, Fabregat-Safont D, Eisenberg T, Gomez J, Plaza A, Sierra-Ramirez A, Perez M, Villanueva-Bermejo D, Fornari T, Loza MI, Herradon G, Hofer SJ, Magnes C, Madeo F, Duerr JS, Pozo OJ, Galindo MI, Del Pino I, Houtkooper RH, Megias D, Viña J, Gomez-Cabrera MC, Fernandez-Marcos PJ. Costa-Machado LF, et al. Among authors: hofer sj. Nat Commun. 2023 May 15;14(1):2779. doi: 10.1038/s41467-023-38410-y. Nat Commun. 2023. PMID: 37188705 Free PMC article.
Autophagy: one more Nobel Prize for yeast.
Zimmermann A, Kainz K, Andryushkova A, Hofer S, Madeo F, Carmona-Gutierrez D. Zimmermann A, et al. Microb Cell. 2016 Dec 5;3(12):579-581. doi: 10.15698/mic2016.12.544. Microb Cell. 2016. PMID: 28357329 Free PMC article.
Yeast as a tool to identify anti-aging compounds.
Zimmermann A, Hofer S, Pendl T, Kainz K, Madeo F, Carmona-Gutierrez D. Zimmermann A, et al. FEMS Yeast Res. 2018 Sep 1;18(6):foy020. doi: 10.1093/femsyr/foy020. FEMS Yeast Res. 2018. PMID: 29905792 Free PMC article. Review.
The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Carmona-Gutierrez D, Zimmermann A, Kainz K, Pietrocola F, Chen G, Maglioni S, Schiavi A, Nah J, Mertel S, Beuschel CB, Castoldi F, Sica V, Trausinger G, Raml R, Sommer C, Schroeder S, Hofer SJ, Bauer MA, Pendl T, Tadic J, Dammbrueck C, Hu Z, Ruckenstuhl C, Eisenberg T, Durand S, Bossut N, Aprahamian F, Abdellatif M, Sedej S, Enot DP, Wolinski H, Dengjel J, Kepp O, Magnes C, Sinner F, Pieber TR, Sadoshima J, Ventura N, Sigrist SJ, Kroemer G, Madeo F. Carmona-Gutierrez D, et al. Among authors: hofer sj. Nat Commun. 2019 Feb 19;10(1):651. doi: 10.1038/s41467-019-08555-w. Nat Commun. 2019. PMID: 30783116 Free PMC article.
Targeting GATA transcription factors - a novel strategy for anti-aging interventions?
Zimmermann A, Kainz K, Hofer SJ, Bauer MA, Schroeder S, Dengjel J, Pietrocola F, Kepp O, Ruckenstuhl C, Eisenberg T, Sigrist SJ, Madeo F, Kroemer G, Carmona-Gutierrez D. Zimmermann A, et al. Among authors: hofer sj. Microb Cell. 2019 May 6;6(5):212-216. doi: 10.15698/mic2019.05.676. Microb Cell. 2019. PMID: 31114793 Free PMC article.
4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects.
Zimmermann A, Kainz K, Hofer SJ, Bauer MA, Schroeder S, Dengjel J, Pietrocola F, Kepp O, Ruckenstuhl C, Eisenberg T, Sigrist SJ, Madeo F, Carmona-Gutierrez D, Kroemer G. Zimmermann A, et al. Among authors: hofer sj. Autophagy. 2019 Sep;15(9):1662-1664. doi: 10.1080/15548627.2019.1632623. Epub 2019 Jun 28. Autophagy. 2019. PMID: 31248332 Free PMC article.
Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.
Stekovic S, Hofer SJ, Tripolt N, Aon MA, Royer P, Pein L, Stadler JT, Pendl T, Prietl B, Url J, Schroeder S, Tadic J, Eisenberg T, Magnes C, Stumpe M, Zuegner E, Bordag N, Riedl R, Schmidt A, Kolesnik E, Verheyen N, Springer A, Madl T, Sinner F, de Cabo R, Kroemer G, Obermayer-Pietsch B, Dengjel J, Sourij H, Pieber TR, Madeo F. Stekovic S, et al. Among authors: hofer sj. Cell Metab. 2019 Sep 3;30(3):462-476.e6. doi: 10.1016/j.cmet.2019.07.016. Epub 2019 Aug 27. Cell Metab. 2019. PMID: 31471173 Free article. Clinical Trial.
Transcriptional and epigenetic control of regulated cell death in yeast.
Zimmermann A, Tadic J, Kainz K, Hofer SJ, Bauer MA, Carmona-Gutierrez D, Madeo F. Zimmermann A, et al. Among authors: hofer sj. Int Rev Cell Mol Biol. 2020;352:55-82. doi: 10.1016/bs.ircmb.2019.12.003. Epub 2020 Jan 13. Int Rev Cell Mol Biol. 2020. PMID: 32334817 Review.
36 results