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Diagnostics to support elimination of lymphatic filariasis-Development of two target product profiles.
Won KY, Gass K, Biamonte M, Dagne DA, Ducker C, Hanna C, Hoerauf A, Lammie PJ, Njenga SM, Noordin R, Ramaiah KD, Ramzy R, Scholte RGC, Solomon AW, Souza AA, Tappero J, Toubali E, Weil GJ, Williams SA, King JD. Won KY, et al. Among authors: hoerauf a. PLoS Negl Trop Dis. 2021 Nov 15;15(11):e0009968. doi: 10.1371/journal.pntd.0009968. eCollection 2021 Nov. PLoS Negl Trop Dis. 2021. PMID: 34780503 Free PMC article.
Filariasis and lymphoedema.
Pfarr KM, Debrah AY, Specht S, Hoerauf A. Pfarr KM, et al. Among authors: hoerauf a. Parasite Immunol. 2009 Nov;31(11):664-72. doi: 10.1111/j.1365-3024.2009.01133.x. Parasite Immunol. 2009. PMID: 19825106 Free PMC article. Review.
Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania.
Kroidl I, Saathof E, Maganga L, Clowes P, Maboko L, Hoerauf A, Makunde WH, Haule A, Mviombo P, Pitter B, Mgeni N, Mabuye J, Kowuor D, Mwingira U, Malecela MN, Löscher T, Hoelscher M. Kroidl I, et al. Among authors: hoerauf a. PLoS Negl Trop Dis. 2016 Apr 12;10(4):e0004618. doi: 10.1371/journal.pntd.0004618. eCollection 2016 Apr. PLoS Negl Trop Dis. 2016. PMID: 27070786 Free PMC article.
Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes.
Prodjinotho UF, von Horn C, Debrah AY, Batsa Debrah L, Albers A, Layland LE, Hoerauf A, Adjobimey T. Prodjinotho UF, et al. Among authors: hoerauf a. PLoS Negl Trop Dis. 2017 Jul 24;11(7):e0005777. doi: 10.1371/journal.pntd.0005777. eCollection 2017 Jul. PLoS Negl Trop Dis. 2017. PMID: 28742098 Free PMC article.
Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.
von Geldern TW, Morton HE, Clark RF, Brown BS, Johnston KL, Ford L, Specht S, Carr RA, Stolarik DF, Ma J, Rieser MJ, Struever D, Frohberger SJ, Koschel M, Ehrens A, Turner JD, Hübner MP, Hoerauf A, Taylor MJ, Ward SA, Marsh K, Kempf DJ. von Geldern TW, et al. Among authors: hoerauf a. PLoS Negl Trop Dis. 2019 Feb 28;13(2):e0007159. doi: 10.1371/journal.pntd.0007159. eCollection 2019 Feb. PLoS Negl Trop Dis. 2019. PMID: 30818326 Free PMC article.
Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.
Taylor MJ, von Geldern TW, Ford L, Hübner MP, Marsh K, Johnston KL, Sjoberg HT, Specht S, Pionnier N, Tyrer HE, Clare RH, Cook DAN, Murphy E, Steven A, Archer J, Bloemker D, Lenz F, Koschel M, Ehrens A, Metuge HM, Chunda VC, Ndongmo Chounna PW, Njouendou AJ, Fombad FF, Carr R, Morton HE, Aljayyoussi G, Hoerauf A, Wanji S, Kempf DJ, Turner JD, Ward SA. Taylor MJ, et al. Among authors: hoerauf a. Sci Transl Med. 2019 Mar 13;11(483):eaau2086. doi: 10.1126/scitranslmed.aau2086. Sci Transl Med. 2019. PMID: 30867321 Free article.
396 results