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Multiomics Characterization of Low-Grade Serous Ovarian Carcinoma Identifies Potential Biomarkers of MEK Inhibitor Sensitivity and Therapeutic Vulnerability.
Shrestha R, Llaurado Fernandez M, Dawson A, Hoenisch J, Volik S, Lin YY, Anderson S, Kim H, Haegert AM, Colborne S, Wong NKY, McConeghy B, Bell RH, Brahmbhatt S, Lee CH, DiMattia GE, Le Bihan S, Morin GB, Collins CC, Carey MS. Shrestha R, et al. Among authors: hoenisch j. Cancer Res. 2021 Apr 1;81(7):1681-1694. doi: 10.1158/0008-5472.CAN-20-2222. Epub 2021 Jan 13. Cancer Res. 2021. PMID: 33441310
Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target.
Fernandez ML, Dawson A, Hoenisch J, Kim H, Bamford S, Salamanca C, DiMattia G, Shepherd T, Cremona M, Hennessy B, Anderson S, Volik S, Collins CC, Huntsman DG, Carey MS. Fernandez ML, et al. Among authors: hoenisch j. Cancer Cell Int. 2019 Jan 8;19:10. doi: 10.1186/s12935-019-0725-1. eCollection 2019. Cancer Cell Int. 2019. PMID: 30636931 Free PMC article.
Hormone receptor expression and outcomes in low-grade serous ovarian carcinoma.
Llaurado Fernandez M, Dawson A, Kim H, Lam N, Russell H, Bruce M, Bittner M, Hoenisch J, Scott SA, Talhouk A, Chiu D, Provencher D, Nourmoussavi M, DiMattia G, Lee CH, Gilks CB, Köbel M, Carey MS. Llaurado Fernandez M, et al. Among authors: hoenisch j. Gynecol Oncol. 2020 Apr;157(1):12-20. doi: 10.1016/j.ygyno.2019.11.029. Epub 2020 Jan 15. Gynecol Oncol. 2020. PMID: 31954537
NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition.
Llaurado Fernandez M, Hijmans EM, Gennissen AMC, Wong NKY, Li S, Wisman GBA, Hamilton A, Hoenisch J, Dawson A, Lee CH, Bittner M, Kim H, DiMattia GE, Lok CAR, Lieftink C, Beijersbergen RL, de Jong S, Carey MS, Bernards R, Berns K. Llaurado Fernandez M, et al. Among authors: hoenisch j. Mol Cancer Ther. 2022 Dec 2;21(12):1862-1874. doi: 10.1158/1535-7163.MCT-22-0004. Mol Cancer Ther. 2022. PMID: 36198031 Free PMC article.
Molecular characterization of low-grade serous ovarian carcinoma identifies genomic aberrations according to hormone receptor expression.
Cheasley D, Fernandez ML, Köbel M, Kim H, Dawson A, Hoenisch J, Bittner M, Chiu DS, Talhouk A, Gilks CB, Jayawardana MW, Pishas KI, Mes-Masson AM, Provencher D, Nigam A, Hacker NF, Gorringe KL, Campbell IG, Carey MS. Cheasley D, et al. Among authors: hoenisch j. NPJ Precis Oncol. 2022 Jun 29;6(1):47. doi: 10.1038/s41698-022-00288-2. NPJ Precis Oncol. 2022. PMID: 35768582 Free PMC article.