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Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
Silveira FF, de Souza JO, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Silveira FF, et al. Among authors: hoelz lvb. Eur J Med Chem. 2021 Jan 1;209:112941. doi: 10.1016/j.ejmech.2020.112941. Epub 2020 Oct 21. Eur J Med Chem. 2021. PMID: 33158577
Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors.
Azeredo LFSP, Coutinho JP, Jabor VAP, Feliciano PR, Nonato MC, Kaiser CR, Menezes CMS, Hammes ASO, Caffarena ER, Hoelz LVB, de Souza NB, Pereira GAN, Cerávolo IP, Krettli AU, Boechat N. Azeredo LFSP, et al. Among authors: hoelz lvb. Eur J Med Chem. 2017 Jan 27;126:72-83. doi: 10.1016/j.ejmech.2016.09.073. Epub 2016 Sep 30. Eur J Med Chem. 2017. PMID: 27744189
New pyrazolopyrimidine derivatives as Leishmania amazonensis arginase inhibitors.
Feitosa LM, da Silva ER, Hoelz LVB, Souza DL, Come JAASS, Cardoso-Santos C, Batista MM, Soeiro MNC, Boechat N, Pinheiro LCS. Feitosa LM, et al. Among authors: hoelz lvb. Bioorg Med Chem. 2019 Jul 15;27(14):3061-3069. doi: 10.1016/j.bmc.2019.05.026. Epub 2019 May 17. Bioorg Med Chem. 2019. PMID: 31176565
Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors.
Gonzaga DTG, Oliveira FH, von Ranke NL, Pinho GQ, Salles JP, Bello ML, Rodrigues CR, Castro HC, de Souza HVCM, Reis CRC, Leme RPP, Mafra JCM, Pinheiro LCS, Hoelz LVB, Boechat N, Faria RX. Gonzaga DTG, et al. Among authors: hoelz lvb. Front Chem. 2019 Apr 30;7:261. doi: 10.3389/fchem.2019.00261. eCollection 2019. Front Chem. 2019. PMID: 31134177 Free PMC article.
Synthesis of benzoylthiourea derivatives and analysis of their antibacterial performance against planktonic Staphylococcus aureus and its biofilms.
Pinheiro LCS, Hoelz LVB, Ferreira MLG, Oliveira LG, Pereira RFA, do Valle AM, André LSP, Scaffo J, Pinheiro FR, Ribeiro TAN, Sachs D, Pascoal ACRF, Boechat N, Aguiar-Alves F. Pinheiro LCS, et al. Among authors: hoelz lvb. Lett Appl Microbiol. 2020 Dec;71(6):645-651. doi: 10.1111/lam.13359. Epub 2020 Sep 22. Lett Appl Microbiol. 2020. PMID: 32725897
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