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Tracing fatty acid metabolism by click chemistry.
ACS Chem Biol. 2012 Dec 21;7(12):2004-11. doi: 10.1021/cb300414v. Epub 2012 Oct 2.
ACS Chem Biol. 2012.
PMID: 22999348
Alkyne lipids as substrates for click chemistry-based in vitro enzymatic assays.
Gaebler A, Milan R, Straub L, Hoelper D, Kuerschner L, Thiele C.
Gaebler A, et al. Among authors: hoelper d.
J Lipid Res. 2013 Aug;54(8):2282-2290. doi: 10.1194/jlr.D038653. Epub 2013 May 23.
J Lipid Res. 2013.
PMID: 23709689
Free PMC article.
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H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2.
Jain SU, Rashoff AQ, Krabbenhoft SD, Hoelper D, Do TJ, Gibson TJ, Lundgren SM, Bondra ER, Deshmukh S, Harutyunyan AS, Juretic N, Jabado N, Harrison MM, Lewis PW.
Jain SU, et al. Among authors: hoelper d.
Mol Cell. 2020 Nov 19;80(4):726-735.e7. doi: 10.1016/j.molcel.2020.09.028. Epub 2020 Oct 12.
Mol Cell. 2020.
PMID: 33049227
Free PMC article.
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S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability of cancer stem cells.
Strekalova E, Malin D, Weisenhorn EMM, Russell JD, Hoelper D, Jain A, Coon JJ, Lewis PW, Cryns VL.
Strekalova E, et al. Among authors: hoelper d.
Breast Cancer Res Treat. 2019 May;175(1):39-50. doi: 10.1007/s10549-019-05146-7. Epub 2019 Feb 2.
Breast Cancer Res Treat. 2019.
PMID: 30712196
Free PMC article.
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Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX.
Hoelper D, Huang H, Jain AY, Patel DJ, Lewis PW.
Hoelper D, et al.
Nat Commun. 2017 Oct 30;8(1):1193. doi: 10.1038/s41467-017-01206-y.
Nat Commun. 2017.
PMID: 29084956
Free PMC article.
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S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3.
Jayaram H, Hoelper D, Jain SU, Cantone N, Lundgren SM, Poy F, Allis CD, Cummings R, Bellon S, Lewis PW.
Jayaram H, et al. Among authors: hoelper d.
Proc Natl Acad Sci U S A. 2016 May 31;113(22):6182-7. doi: 10.1073/pnas.1605523113. Epub 2016 May 16.
Proc Natl Acad Sci U S A. 2016.
PMID: 27185940
Free PMC article.
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Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.
Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW.
Lu C, et al. Among authors: hoelper d.
Science. 2016 May 13;352(6287):844-9. doi: 10.1126/science.aac7272.
Science. 2016.
PMID: 27174990
Free PMC article.
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