Hoehn KL - Search Results

1

Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1.

Du X, Zhang Y, Jo SR, Liu X, Qi Y, Osborne B, Byrne FL, Smith GC, Turner N, Hoehn KL, Brown AJ, Yang H. Du X, et al. Among authors: hoehn kl. Biochem J. 2015 Oct 15;471(2):243-53. doi: 10.1042/BJ20150602. Epub 2015 Aug 17. Biochem J. 2015. PMID: 26283546

2

Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents.

Turner N, Bruce CR, Beale SM, Hoehn KL, So T, Rolph MS, Cooney GJ. Turner N, et al. Among authors: hoehn kl. Diabetes. 2007 Aug;56(8):2085-92. doi: 10.2337/db07-0093. Epub 2007 May 22. Diabetes. 2007. PMID: 17519422

3

IRS1-independent defects define major nodes of insulin resistance.

Hoehn KL, Hohnen-Behrens C, Cederberg A, Wu LE, Turner N, Yuasa T, Ebina Y, James DE. Hoehn KL, et al. Cell Metab. 2008 May;7(5):421-33. doi: 10.1016/j.cmet.2008.04.005. Cell Metab. 2008. PMID: 18460333 Free PMC article.

4

Insulin resistance is a cellular antioxidant defense mechanism.

Hoehn KL, Salmon AB, Hohnen-Behrens C, Turner N, Hoy AJ, Maghzal GJ, Stocker R, Van Remmen H, Kraegen EW, Cooney GJ, Richardson AR, James DE. Hoehn KL, et al. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17787-92. doi: 10.1073/pnas.0902380106. Epub 2009 Sep 30. Proc Natl Acad Sci U S A. 2009. PMID: 19805130 Free PMC article.

5

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity.

Hoehn KL, Turner N, Swarbrick MM, Wilks D, Preston E, Phua Y, Joshi H, Furler SM, Larance M, Hegarty BD, Leslie SJ, Pickford R, Hoy AJ, Kraegen EW, James DE, Cooney GJ. Hoehn KL, et al. Cell Metab. 2010 Jan;11(1):70-6. doi: 10.1016/j.cmet.2009.11.008. Cell Metab. 2010. PMID: 20074529 Free PMC article.

6

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle.

Taddeo EP, Laker RC, Breen DS, Akhtar YN, Kenwood BM, Liao JA, Zhang M, Fazakerley DJ, Tomsig JL, Harris TE, Keller SR, Chow JD, Lynch KR, Chokki M, Molkentin JD, Turner N, James DE, Yan Z, Hoehn KL. Taddeo EP, et al. Among authors: hoehn kl. Mol Metab. 2013 Nov 26;3(2):124-34. doi: 10.1016/j.molmet.2013.11.003. eCollection 2014 Apr. Mol Metab. 2013. PMID: 24634818 Free PMC article.

7

Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.

Chow JD, Lawrence RT, Healy ME, Dominy JE, Liao JA, Breen DS, Byrne FL, Kenwood BM, Lackner C, Okutsu S, Mas VR, Caldwell SH, Tomsig JL, Cooney GJ, Puigserver PB, Turner N, James DE, Villén J, Hoehn KL. Chow JD, et al. Among authors: hoehn kl. Mol Metab. 2014 Mar 12;3(4):419-31. doi: 10.1016/j.molmet.2014.02.004. eCollection 2014 Jul. Mol Metab. 2014. PMID: 24944901 Free PMC article.

8

Metabolic vulnerabilities in endometrial cancer.

Byrne FL, Poon IK, Modesitt SC, Tomsig JL, Chow JD, Healy ME, Baker WD, Atkins KA, Lancaster JM, Marchion DC, Moley KH, Ravichandran KS, Slack-Davis JK, Hoehn KL. Byrne FL, et al. Among authors: hoehn kl. Cancer Res. 2014 Oct 15;74(20):5832-45. doi: 10.1158/0008-5472.CAN-14-0254. Epub 2014 Sep 9. Cancer Res. 2014. PMID: 25205105

9

Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine.

Healy ME, Chow JD, Byrne FL, Breen DS, Leitinger N, Li C, Lackner C, Caldwell SH, Hoehn KL. Healy ME, et al. Among authors: hoehn kl. J Hepatol. 2015 Mar;62(3):599-606. doi: 10.1016/j.jhep.2014.10.024. Epub 2014 Oct 23. J Hepatol. 2015. PMID: 25450719 Free PMC article.

10

Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.

Kashatus JA, Nascimento A, Myers LJ, Sher A, Byrne FL, Hoehn KL, Counter CM, Kashatus DF. Kashatus JA, et al. Among authors: hoehn kl. Mol Cell. 2015 Feb 5;57(3):537-51. doi: 10.1016/j.molcel.2015.01.002. Mol Cell. 2015. PMID: 25658205 Free PMC article.

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