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The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis.
Shmuel-Galia L, Humphries F, Vierbuchen T, Jiang Z, Santos N, Johnson J, Shklyar B, Joannas L, Mustone N, Sherman S, Ward D, Houghton J, Baer CE, O'Hara A, Henao-Mejia J, Hoebe K, Fitzgerald KA. Shmuel-Galia L, et al. Among authors: hoebe k. Cell Metab. 2023 Aug 8;35(8):1441-1456.e9. doi: 10.1016/j.cmet.2023.06.019. Epub 2023 Jul 25. Cell Metab. 2023. PMID: 37494932
The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2.
Vierbuchen T, Agarwal S, Johnson JL, Galia L, Lei X, Stein K, Olagnier D, Gaede KI, Herzmann C, Holm CK, Heine H, Pai A, O'Hara Hall A, Hoebe K, Fitzgerald KA. Vierbuchen T, et al. Among authors: hoebe k. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213715120. doi: 10.1073/pnas.2213715120. Epub 2022 Dec 28. Proc Natl Acad Sci U S A. 2023. PMID: 36577072 Free PMC article.
Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease.
Johnson JL, Sargsyan D, Neiman EM, Hart A, Stojmirovic A, Kosoy R, Irizar H, Suárez-Fariñas M, Song WM, Argmann C, Avey S, Shmuel-Galia L, Vierbuchen T, Bongers G, Sun Y, Edelstein L, Perrigoue J, Towne JE, Hall AO, Fitzgerald KA, Hoebe K. Johnson JL, et al. Among authors: hoebe k. JCI Insight. 2024 Feb 8;9(3):e168988. doi: 10.1172/jci.insight.168988. JCI Insight. 2024. PMID: 38329124 Free PMC article.
PIR-B Regulates CD4+ IL17a+ T-Cell Survival and Restricts T-Cell-Dependent Intestinal Inflammatory Responses.
Uddin J, Tomar S, Sharma A, Waggoner L, Ganesan V, Marella S, Yang Y, Noah T, Vanoni S, Patterson A, Zeng C, Foster PS, Newberry R, Bishu S, Kao JY, Rosen MJ, Denson L, King PD, Hoebe K, Divanovic S, Munitz A, Hogan SP. Uddin J, et al. Among authors: hoebe k. Cell Mol Gastroenterol Hepatol. 2021;12(4):1479-1502. doi: 10.1016/j.jcmgh.2021.06.013. Epub 2021 Jul 6. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34242819 Free PMC article.
GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension.
Drzewiecki K, Choi J, Brancale J, Leney-Greene MA, Sari S, Dalgiç B, Ünlüsoy Aksu A, Evirgen Şahin G, Ozen A, Baris S, Karakoc-Aydiner E, Jain D, Kleiner D, Schmalz M, Radhakrishnan K, Zhang J, Hoebe K, Su HC, Pereira JP, Lenardo MJ, Lifton RP, Vilarinho S. Drzewiecki K, et al. Among authors: hoebe k. J Exp Med. 2021 Jul 5;218(7):e20201745. doi: 10.1084/jem.20201745. Epub 2021 May 6. J Exp Med. 2021. PMID: 33956074 Free PMC article.
94 results