Hodson C - Search Results

1

Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability.

Hodson C, Low JKK, van Twest S, Jones SE, Swuec P, Murphy V, Tsukada K, Fawkes M, Bythell-Douglas R, Davies A, Holien JK, O'Rourke JJ, Parker BL, Glaser A, Parker MW, Mackay JP, Blackford AN, Costa A, Deans AJ. Hodson C, et al. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2109093119. doi: 10.1073/pnas.2109093119. Proc Natl Acad Sci U S A. 2022. PMID: 35115399 Free PMC article.

2

The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair.

Vuono EA, Mukherjee A, Vierra DA, Adroved MM, Hodson C, Deans AJ, Howlett NG. Vuono EA, et al. Among authors: hodson c. Sci Rep. 2016 Nov 7;6:36439. doi: 10.1038/srep36439. Sci Rep. 2016. PMID: 27819275 Free PMC article.

3

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway.

van Twest S, Murphy VJ, Hodson C, Tan W, Swuec P, O'Rourke JJ, Heierhorst J, Crismani W, Deans AJ. van Twest S, et al. Among authors: hodson c. Mol Cell. 2017 Jan 19;65(2):247-259. doi: 10.1016/j.molcel.2016.11.005. Epub 2016 Dec 13. Mol Cell. 2017. PMID: 27986371 Free article.

4

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops.

Silva B, Pentz R, Figueira AM, Arora R, Lee YW, Hodson C, Wischnewski H, Deans AJ, Azzalin CM. Silva B, et al. Among authors: hodson c. Nat Commun. 2019 May 28;10(1):2253. doi: 10.1038/s41467-019-10179-z. Nat Commun. 2019. PMID: 31138795 Free PMC article.

5

ATP-dependent helicase activity is dispensable for the physiological functions of Recql4.

Castillo-Tandazo W, Smeets MF, Murphy V, Liu R, Hodson C, Heierhorst J, Deans AJ, Walkley CR. Castillo-Tandazo W, et al. Among authors: hodson c. PLoS Genet. 2019 Jul 5;15(7):e1008266. doi: 10.1371/journal.pgen.1008266. eCollection 2019 Jul. PLoS Genet. 2019. PMID: 31276497 Free PMC article.

6

Branchpoint translocation by fork remodelers as a general mechanism of R-loop removal.

Hodson C, van Twest S, Dylewska M, O'Rourke JJ, Tan W, Murphy VJ, Walia M, Abbouche L, Nieminuszczy J, Dunn E, Bythell-Douglas R, Heierhorst J, Niedzwiedz W, Deans AJ. Hodson C, et al. Cell Rep. 2022 Dec 6;41(10):111749. doi: 10.1016/j.celrep.2022.111749. Cell Rep. 2022. PMID: 36476850 Free article.

7

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.

Mollah ZUA, Quah HS, Graham KL, Jhala G, Krishnamurthy B, Dharma JFM, Chee J, Trivedi PM, Pappas EG, Mackin L, Chu EPF, Akazawa S, Fynch S, Hodson C, Deans AJ, Trapani JA, Chong MMW, Bird PI, Brodnicki TC, Thomas HE, Kay TWH. Mollah ZUA, et al. Among authors: hodson c. Diabetes. 2017 Dec;66(12):3041-3050. doi: 10.2337/db17-0517. Epub 2017 Jul 21. Diabetes. 2017. PMID: 28733313

8

Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway.

Hodson C, Cole AR, Lewis LP, Miles JA, Purkiss A, Walden H. Hodson C, et al. J Biol Chem. 2011 Sep 16;286(37):32628-37. doi: 10.1074/jbc.M111.244632. Epub 2011 Jul 20. J Biol Chem. 2011. PMID: 21775430 Free PMC article.

9

Towards a molecular understanding of the fanconi anemia core complex.

Hodson C, Walden H. Hodson C, et al. Anemia. 2012;2012:926787. doi: 10.1155/2012/926787. Epub 2012 May 22. Anemia. 2012. PMID: 22675617 Free PMC article.

10

Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection.

Hodson C, Purkiss A, Miles JA, Walden H. Hodson C, et al. Structure. 2014 Feb 4;22(2):337-44. doi: 10.1016/j.str.2013.12.004. Epub 2014 Jan 2. Structure. 2014. PMID: 24389026 Free PMC article.

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