Hodgkinson JT - Search Results

1

Siderophore-Antibiotic Conjugate Design: New Drugs for Bad Bugs?

Negash KH, Norris JKS, Hodgkinson JT. Negash KH, et al. Among authors: hodgkinson jt. Molecules. 2019 Sep 11;24(18):3314. doi: 10.3390/molecules24183314. Molecules. 2019. PMID: 31514464 Free PMC article. Review.

2

Design and synthesis of a biotinylated chemical probe for detecting the molecular targets of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin.

Baker YR, Galloway WR, Hodgkinson JT, Spring DR. Baker YR, et al. Among authors: hodgkinson jt. Molecules. 2013 Sep 25;18(10):11783-96. doi: 10.3390/molecules181011783. Molecules. 2013. PMID: 24071985 Free PMC article.

3

The design and synthesis of an antibacterial phenothiazine-siderophore conjugate.

Tarapdar A, Norris JKS, Sampson O, Mukamolova G, Hodgkinson JT. Tarapdar A, et al. Among authors: hodgkinson jt. Beilstein J Org Chem. 2018 Oct 16;14:2646-2650. doi: 10.3762/bjoc.14.242. eCollection 2018. Beilstein J Org Chem. 2018. PMID: 30410626 Free PMC article.

4

PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes.

Smalley JP, Adams GE, Millard CJ, Song Y, Norris JKS, Schwabe JWR, Cowley SM, Hodgkinson JT. Smalley JP, et al. Among authors: hodgkinson jt. Chem Commun (Camb). 2020 Apr 21;56(32):4476-4479. doi: 10.1039/d0cc01485k. Chem Commun (Camb). 2020. PMID: 32201871 Free PMC article.

5

Bifunctional HDAC Therapeutics: One Drug to Rule Them All?

Smalley JP, Cowley SM, Hodgkinson JT. Smalley JP, et al. Among authors: hodgkinson jt. Molecules. 2020 Sep 24;25(19):4394. doi: 10.3390/molecules25194394. Molecules. 2020. PMID: 32987782 Free PMC article. Review.

6

Novel and efficient copper-catalysed synthesis of nitrogen-linked medium-ring biaryls.

Kenwright JL, Galloway WR, Blackwell DT, Isidro-Llobet A, Hodgkinson J, Wortmann L, Bowden SD, Welch M, Spring DR. Kenwright JL, et al. Chemistry. 2011 Mar 1;17(10):2981-6. doi: 10.1002/chem.201002093. Epub 2011 Feb 2. Chemistry. 2011. PMID: 21290435

7

Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa.

Hodgkinson JT, Galloway WR, Wright M, Mati IK, Nicholson RL, Welch M, Spring DR. Hodgkinson JT, et al. Org Biomol Chem. 2012 Aug 14;10(30):6032-44. doi: 10.1039/c2ob25198a. Epub 2012 Apr 13. Org Biomol Chem. 2012. PMID: 22499353

8

Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics.

Morkunas B, Galloway WR, Wright M, Ibbeson BM, Hodgkinson JT, O'Connell KM, Bartolucci N, Della Valle M, Welch M, Spring DR. Morkunas B, et al. Among authors: hodgkinson jt. Org Biomol Chem. 2012 Nov 14;10(42):8452-64. doi: 10.1039/c2ob26501j. Epub 2012 Sep 27. Org Biomol Chem. 2012. PMID: 23014532

9

PROTAC chemical probes for histone deacetylase enzymes.

Patel U, Smalley JP, Hodgkinson JT. Patel U, et al. Among authors: hodgkinson jt. RSC Chem Biol. 2023 Jul 27;4(9):623-634. doi: 10.1039/d3cb00105a. eCollection 2023 Aug 30. RSC Chem Biol. 2023. PMID: 37654508 Free PMC article. Review.

10

A 'click' chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras.

Cross JM, Coulson ME, Smalley JP, Pytel WA, Ismail O, Trory JS, Cowley SM, Hodgkinson JT. Cross JM, et al. Among authors: hodgkinson jt. RSC Med Chem. 2022 Nov 1;13(12):1634-1639. doi: 10.1039/d2md00199c. eCollection 2022 Dec 14. RSC Med Chem. 2022. PMID: 36545434 Free PMC article.

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