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Armored modified vaccinia Ankara in cancer immunotherapy.
Atay C, Medina-Echeverz J, Hochrein H, Suter M, Hinterberger M. Atay C, et al. Among authors: hochrein h. Int Rev Cell Mol Biol. 2023;379:87-142. doi: 10.1016/bs.ircmb.2023.05.003. Epub 2023 May 31. Int Rev Cell Mol Biol. 2023. PMID: 37541728 Review.
Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication.
Hinterberger M, Endt K, Bathke B, Habjan M, Heiseke A, Schweneker M, Von Rohrscheidt J, Atay C, Chaplin P, Kalla M, Hausmann J, Schmittwolf C, Lauterbach H, Volkmann A, Hochrein H, Medina-Echeverz J. Hinterberger M, et al. Among authors: hochrein h. Sci Rep. 2023 Mar 30;13(1):5162. doi: 10.1038/s41598-023-32060-2. Sci Rep. 2023. PMID: 36997583 Free PMC article.
Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis.
Bella Á, Arrizabalaga L, Di Trani CA, Gonzalez-Gomariz J, Gomar C, Russo-Cabrera JS, Olivera I, Cirella A, Fernandez-Sendin M, Alvarez M, Teijeira A, Atay C, Medina-Echeverz J, Hinterberger M, Hochrein H, Melero I, Berraondo P, Aranda F. Bella Á, et al. Among authors: hochrein h. J Immunother Cancer. 2023 Nov;11(11):e006702. doi: 10.1136/jitc-2023-006702. J Immunother Cancer. 2023. PMID: 37918917 Free PMC article.
Synergistic antitumor response with recombinant modified virus Ankara armed with CD40L and CD137L against peritoneal carcinomatosis.
Bella Á, Arrizabalaga L, Di Trani CA, Cirella A, Fernandez-Sendin M, Gomar C, Russo-Cabrera JS, Rodríguez I, González-Gomariz J, Alvarez M, Teijeira Á, Medina-Echeverz J, Hinterberger M, Hochrein H, Melero I, Berraondo P, Aranda F. Bella Á, et al. Among authors: hochrein h. Oncoimmunology. 2022 Jul 13;11(1):2098657. doi: 10.1080/2162402X.2022.2098657. eCollection 2022. Oncoimmunology. 2022. PMID: 35859732 Free PMC article.
A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques.
Volkmann A, Koopman G, Mooij P, Verschoor EJ, Verstrepen BE, Bogers WMJM, Idorn M, Paludan SR, Vang S, Nielsen MA, Sander AF, Schmittwolf C, Hochrein H, Chaplin P. Volkmann A, et al. Among authors: hochrein h. Front Immunol. 2022 Apr 5;13:857440. doi: 10.3389/fimmu.2022.857440. eCollection 2022. Front Immunol. 2022. PMID: 35479095 Free PMC article.
Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations.
Pang ES, Daraj G, Balka KR, De Nardo D, Macri C, Hochrein H, Masterman KA, Tan PS, Shoppee A, Magill Z, Jahan N, Bafit M, Zhan Y, Kile BT, Lawlor KE, Radford KJ, Wright MD, O'Keeffe M. Pang ES, et al. Among authors: hochrein h. Front Immunol. 2022 Feb 25;13:794776. doi: 10.3389/fimmu.2022.794776. eCollection 2022. Front Immunol. 2022. PMID: 35281062 Free PMC article.
Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory.
Hinterberger M, Giessel R, Fiore G, Graebnitz F, Bathke B, Wennier S, Chaplin P, Melero I, Suter M, Lauterbach H, Berraondo P, Hochrein H, Medina-Echeverz J. Hinterberger M, et al. Among authors: hochrein h. J Immunother Cancer. 2021 Feb;9(2):e001586. doi: 10.1136/jitc-2020-001586. J Immunother Cancer. 2021. PMID: 33579736 Free PMC article.
Human monkeypox - After 40 years, an unintended consequence of smallpox eradication.
Simpson K, Heymann D, Brown CS, Edmunds WJ, Elsgaard J, Fine P, Hochrein H, Hoff NA, Green A, Ihekweazu C, Jones TC, Lule S, Maclennan J, McCollum A, Mühlemann B, Nightingale E, Ogoina D, Ogunleye A, Petersen B, Powell J, Quantick O, Rimoin AW, Ulaeato D, Wapling A. Simpson K, et al. Among authors: hochrein h. Vaccine. 2020 Jul 14;38(33):5077-5081. doi: 10.1016/j.vaccine.2020.04.062. Epub 2020 May 13. Vaccine. 2020. PMID: 32417140 Free PMC article.
302 results