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Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.
Thery F, Martina L, Asselman C, Zhang Y, Vessely M, Repo H, Sedeyn K, Moschonas GD, Bredow C, Teo QW, Zhang J, Leandro K, Eggermont D, De Sutter D, Boucher K, Hochepied T, Festjens N, Callewaert N, Saelens X, Dermaut B, Knobeloch KP, Beling A, Sanyal S, Radoshevich L, Eyckerman S, Impens F. Thery F, et al. Among authors: hochepied t. Nat Commun. 2021 Oct 1;12(1):5772. doi: 10.1038/s41467-021-26061-w. Nat Commun. 2021. PMID: 34599178 Free PMC article.
Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice.
Thoonen R, Cauwels A, Decaluwe K, Geschka S, Tainsh RE, Delanghe J, Hochepied T, De Cauwer L, Rogge E, Voet S, Sips P, Karas RH, Bloch KD, Vuylsteke M, Stasch JP, Van de Voorde J, Buys ES, Brouckaert P. Thoonen R, et al. Among authors: hochepied t. Nat Commun. 2015 Oct 7;6:8482. doi: 10.1038/ncomms9482. Nat Commun. 2015. PMID: 26442659 Free PMC article.
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.
Hoste E, Lecomte K, Annusver K, Vandamme N, Roels J, Maschalidi S, Verboom L, Vikkula HK, Sze M, Van Hove L, Verstaen K, Martens A, Hochepied T, Saeys Y, Ravichandran K, Kasper M, van Loo G. Hoste E, et al. Among authors: hochepied t. Nat Commun. 2021 Oct 8;12(1):5913. doi: 10.1038/s41467-021-25944-2. Nat Commun. 2021. PMID: 34625556 Free PMC article.
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, Voet S, Deelen L, Sze M, Vikkula H, Slowicka K, Hochepied T, Iliaki K, Wullaert A, Janssens S, Lamkanfi M, Beyaert R, Armaka M, Bertrand MJM, van Loo G. Martens A, et al. Among authors: hochepied t. Nat Immunol. 2020 Apr;21(4):381-387. doi: 10.1038/s41590-020-0621-9. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205881
Caspase-14 protects against epidermal UVB photodamage and water loss.
Denecker G, Hoste E, Gilbert B, Hochepied T, Ovaere P, Lippens S, Van den Broecke C, Van Damme P, D'Herde K, Hachem JP, Borgonie G, Presland RB, Schoonjans L, Libert C, Vandekerckhove J, Gevaert K, Vandenabeele P, Declercq W. Denecker G, et al. Among authors: hochepied t. Nat Cell Biol. 2007 Jun;9(6):666-74. doi: 10.1038/ncb1597. Epub 2007 May 21. Nat Cell Biol. 2007. PMID: 17515931
NLRP2 controls age-associated maternal fertility.
Kuchmiy AA, D'Hont J, Hochepied T, Lamkanfi M. Kuchmiy AA, et al. Among authors: hochepied t. J Exp Med. 2016 Dec 12;213(13):2851-2860. doi: 10.1084/jem.20160900. Epub 2016 Nov 23. J Exp Med. 2016. PMID: 27881734 Free PMC article.
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