Hobbs AJ - Search Results

1

Vascular K_ATP channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia.

Aziz Q, Chen J, Moyes AJ, Li Y, Anderson NA, Ang R, Aksentijevic D, Sebastian S, Hobbs AJ, Thiemermann C, Tinker A. Aziz Q, et al. Among authors: hobbs aj. J Mol Med (Berl). 2020 Aug;98(8):1149-1160. doi: 10.1007/s00109-020-01946-3. Epub 2020 Jul 6. J Mol Med (Berl). 2020. PMID: 32632751 Free PMC article.

2

Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice.

Milsom AB, Patel NS, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ, Cuzzocrea S, Hobbs AJ, Thiemermann C, Ahluwalia A. Milsom AB, et al. Among authors: hobbs aj. Nitric Oxide. 2010 Feb 15;22(2):141-8. doi: 10.1016/j.niox.2009.10.010. Epub 2009 Nov 3. Nitric Oxide. 2010. PMID: 19892029

3

Endothelial C-type natriuretic peptide maintains vascular homeostasis.

Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ, Rebstock AS, Worthington RJ, Simone MI, Mota F, Rivilla F, Vallejo S, Peiró C, Sánchez Ferrer CF, Djordjevic S, Caulfield MJ, MacAllister RJ, Selwood DL, Ahluwalia A, Hobbs AJ. Moyes AJ, et al. Among authors: hobbs aj. J Clin Invest. 2014 Sep;124(9):4039-51. doi: 10.1172/JCI74281. Epub 2014 Aug 8. J Clin Invest. 2014. PMID: 25105365 Free PMC article.

4

Raised arterial blood pressure in neurokinin-1 receptor-deficient mice (NK1R(-/-) ): evidence for a neural rather than a vascular mechanism.

Moyes AJ, Stanford SC, Hosford PS, Hobbs AJ, Ramage AG. Moyes AJ, et al. Among authors: hobbs aj. Exp Physiol. 2016 May 1;101(5):588-98. doi: 10.1113/EP085347. Epub 2016 Apr 9. Exp Physiol. 2016. PMID: 26876733 Free article.

5

IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.

Chen J, Kieswich JE, Chiazza F, Moyes AJ, Gobbetti T, Purvis GS, Salvatori DC, Patel NS, Perretti M, Hobbs AJ, Collino M, Yaqoob MM, Thiemermann C. Chen J, et al. Among authors: hobbs aj. J Am Soc Nephrol. 2017 Jan;28(1):94-105. doi: 10.1681/ASN.2015060670. Epub 2016 May 6. J Am Soc Nephrol. 2017. PMID: 27153924 Free PMC article.

6

Functional pharmacological characterization of SER100 in cardiovascular health and disease.

Villar IC, Bubb KJ, Moyes AJ, Steiness E, Gulbrandsen T, Levy FO, Hobbs AJ. Villar IC, et al. Among authors: hobbs aj. Br J Pharmacol. 2016 Dec;173(23):3386-3401. doi: 10.1111/bph.13634. Epub 2016 Nov 1. Br J Pharmacol. 2016. PMID: 27667485 Free PMC article.

7

Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure.

Baliga RS, Preedy MEJ, Dukinfield MS, Chu SM, Aubdool AA, Bubb KJ, Moyes AJ, Tones MA, Hobbs AJ. Baliga RS, et al. Among authors: hobbs aj. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7428-E7437. doi: 10.1073/pnas.1800996115. Epub 2018 Jul 16. Proc Natl Acad Sci U S A. 2018. PMID: 30012589 Free PMC article.

8

Endothelial C-Type Natriuretic Peptide Is a Critical Regulator of Angiogenesis and Vascular Remodeling.

Bubb KJ, Aubdool AA, Moyes AJ, Lewis S, Drayton JP, Tang O, Mehta V, Zachary IC, Abraham DJ, Tsui J, Hobbs AJ. Bubb KJ, et al. Among authors: hobbs aj. Circulation. 2019 Mar 26;139(13):1612-1628. doi: 10.1161/CIRCULATIONAHA.118.036344. Circulation. 2019. PMID: 30586761 Free PMC article.

9

Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial.

Hobbs AJ, Moyes AJ, Baliga RS, Ghedia D, Ochiel R, Sylvestre Y, Doré CJ, Chowdhury K, Maclagan K, Quartly HL, Sofat R, Smit A, Schreiber BE, Coghlan GJ, MacAllister RJ. Hobbs AJ, et al. Br J Pharmacol. 2019 May;176(9):1251-1267. doi: 10.1111/bph.14621. Epub 2019 Mar 31. Br J Pharmacol. 2019. PMID: 30761523 Free PMC article. Clinical Trial.

10

C-type natriuretic peptide co-ordinates cardiac structure and function.

Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS, Hobbs AJ. Moyes AJ, et al. Among authors: hobbs aj. Eur Heart J. 2020 Mar 1;41(9):1006-1020. doi: 10.1093/eurheartj/ehz093. Eur Heart J. 2020. PMID: 30903134 Free PMC article.

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