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Publisher Correction: Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Black SJ, Ozdemir AY, Kashkina E, Kent T, Rusanov T, Ristic D, Shin Y, Suma A, Hoang T, Chandramouly G, Siddique LA, Borisonnik N, Sullivan-Reed K, Mallon JS, Skorski T, Carnevale V, Murakami KS, Wyman C, Pomerantz RT. Black SJ, et al. Among authors: hoang t. Nat Commun. 2020 Apr 9;11(1):1831. doi: 10.1038/s41467-020-15551-y. Nat Commun. 2020. PMID: 32273507 Free PMC article.
The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.
Mateos-Gomez PA, Kent T, Deng SK, McDevitt S, Kashkina E, Hoang TM, Pomerantz RT, Sfeir A. Mateos-Gomez PA, et al. Among authors: hoang tm. Nat Struct Mol Biol. 2017 Dec;24(12):1116-1123. doi: 10.1038/nsmb.3494. Epub 2017 Oct 23. Nat Struct Mol Biol. 2017. PMID: 29058711 Free PMC article.
One-step enzymatic modification of RNA 3' termini using polymerase θ.
Thomas C, Rusanov T, Hoang T, Augustin T, Kent T, Gaspar I, Pomerantz RT. Thomas C, et al. Among authors: hoang t. Nucleic Acids Res. 2019 Apr 23;47(7):3272-3283. doi: 10.1093/nar/gkz029. Nucleic Acids Res. 2019. PMID: 30818397 Free PMC article.
Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Black SJ, Ozdemir AY, Kashkina E, Kent T, Rusanov T, Ristic D, Shin Y, Suma A, Hoang T, Chandramouly G, Siddique LA, Borisonnik N, Sullivan-Reed K, Mallon JS, Skorski T, Carnevale V, Murakami KS, Wyman C, Pomerantz RT. Black SJ, et al. Among authors: hoang t. Nat Commun. 2019 Sep 27;10(1):4423. doi: 10.1038/s41467-019-12272-9. Nat Commun. 2019. PMID: 31562312 Free PMC article.
Polθ reverse transcribes RNA and promotes RNA-templated DNA repair.
Chandramouly G, Zhao J, McDevitt S, Rusanov T, Hoang T, Borisonnik N, Treddinick T, Lopezcolorado FW, Kent T, Siddique LA, Mallon J, Huhn J, Shoda Z, Kashkina E, Brambati A, Stark JM, Chen XS, Pomerantz RT. Chandramouly G, et al. Among authors: hoang t. Sci Adv. 2021 Jun 11;7(24):eabf1771. doi: 10.1126/sciadv.abf1771. Print 2021 Jun. Sci Adv. 2021. PMID: 34117057 Free PMC article.
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors.
Fried W, Tyagi M, Minakhin L, Chandramouly G, Tredinnick T, Ramanjulu M, Auerbacher W, Calbert M, Rusanov T, Hoang T, Borisonnik N, Betsch R, Krais JJ, Wang Y, Vekariya UM, Gordon J, Morton G, Kent T, Skorski T, Johnson N, Childers W, Chen XS, Pomerantz RT. Fried W, et al. Among authors: hoang t. Nat Commun. 2024 Apr 5;15(1):2862. doi: 10.1038/s41467-024-46593-1. Nat Commun. 2024. PMID: 38580648 Free PMC article.
The MexTAg collaborative cross: host genetics affects asbestos related disease latency, but has little influence once tumours develop.
Fisher SA, Patrick K, Hoang T, Marcq E, Behrouzfar K, Young S, Miller TJ, Robinson BWS, Bueno R, Nowak AK, Lesterhuis WJ, Morahan G, Lake RA. Fisher SA, et al. Among authors: hoang t. Front Toxicol. 2024 Apr 17;6:1373003. doi: 10.3389/ftox.2024.1373003. eCollection 2024. Front Toxicol. 2024. PMID: 38694815 Free PMC article.
1,782 results