Hoang QQ - Search Results

1

Roc, the G-domain of the Parkinson's disease-associated protein LRRK2.

Park Y, Liao J, Hoang QQ. Park Y, et al. Among authors: hoang qq. Trends Biochem Sci. 2022 Dec;47(12):1038-1047. doi: 10.1016/j.tibs.2022.06.009. Epub 2022 Jul 12. Trends Biochem Sci. 2022. PMID: 35840518 Free PMC article. Review.

2

Roco Proteins and the Parkinson's Disease-Associated LRRK2.

Liao J, Hoang QQ. Liao J, et al. Among authors: hoang qq. Int J Mol Sci. 2018 Dec 17;19(12):4074. doi: 10.3390/ijms19124074. Int J Mol Sci. 2018. PMID: 30562929 Free PMC article. Review.

3

The Parkinson's disease-associated mutation N1437H impairs conformational dynamics in the G domain of LRRK2.

Huang X, Wu C, Park Y, Long X, Hoang QQ, Liao J. Huang X, et al. Among authors: hoang qq. FASEB J. 2019 Apr;33(4):4814-4823. doi: 10.1096/fj.201802031R. Epub 2018 Dec 28. FASEB J. 2019. PMID: 30592623 Free PMC article.

4

Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.

Wu CX, Liao J, Park Y, Reed X, Engel VA, Hoang NC, Takagi Y, Johnson SM, Wang M, Federici M, Nichols RJ, Sanishvili R, Cookson MR, Hoang QQ. Wu CX, et al. Among authors: hoang qq. J Biol Chem. 2019 Apr 12;294(15):5907-5913. doi: 10.1074/jbc.RA119.007631. Epub 2019 Feb 22. J Biol Chem. 2019. PMID: 30796162 Free PMC article.

5

Parkinson disease-associated mutation R1441H in LRRK2 prolongs the "active state" of its GTPase domain.

Liao J, Wu CX, Burlak C, Zhang S, Sahm H, Wang M, Zhang ZY, Vogel KW, Federici M, Riddle SM, Nichols RJ, Liu D, Cookson MR, Stone TA, Hoang QQ. Liao J, et al. Among authors: hoang qq. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4055-60. doi: 10.1073/pnas.1323285111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591621 Free PMC article.

6

Combating Parkinson's disease-associated toxicity by modulating proteostasis.

Park Y, Hoang QQ. Park Y, et al. Among authors: hoang qq. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):803-804. doi: 10.1073/pnas.1620082114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096350 Free PMC article. No abstract available.

7

A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson's disease.

Fevga C, Park Y, Lohmann E, Kievit AJ, Breedveld GJ, Ferraro F, de Boer L, van Minkelen R, Hanagasi H, Boon A, Wang W, Petsko GA, Hoang QQ, Emre M, Bonifati V. Fevga C, et al. Among authors: hoang qq. Parkinsonism Relat Disord. 2021 Aug;89:63-72. doi: 10.1016/j.parkreldis.2021.06.023. Epub 2021 Jun 29. Parkinsonism Relat Disord. 2021. PMID: 34229155 Free PMC article.

8

HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.

Stevens M, Abdeen S, Salim N, Ray AM, Washburn A, Chitre S, Sivinski J, Park Y, Hoang QQ, Chapman E, Johnson SM. Stevens M, et al. Among authors: hoang qq. Bioorg Med Chem Lett. 2019 May 1;29(9):1106-1112. doi: 10.1016/j.bmcl.2019.02.028. Epub 2019 Feb 28. Bioorg Med Chem Lett. 2019. PMID: 30852084 Free PMC article.

9

Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.

Washburn A, Abdeen S, Ovechkina Y, Ray AM, Stevens M, Chitre S, Sivinski J, Park Y, Johnson J, Hoang QQ, Chapman E, Parish T, Johnson SM. Washburn A, et al. Among authors: hoang qq. Bioorg Med Chem Lett. 2019 Jul 1;29(13):1665-1672. doi: 10.1016/j.bmcl.2019.04.034. Epub 2019 Apr 24. Bioorg Med Chem Lett. 2019. PMID: 31047750 Free PMC article.

10

Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs.

Stevens M, Howe C, Ray AM, Washburn A, Chitre S, Sivinski J, Park Y, Hoang QQ, Chapman E, Johnson SM. Stevens M, et al. Among authors: hoang qq. Bioorg Med Chem. 2020 Nov 15;28(22):115710. doi: 10.1016/j.bmc.2020.115710. Epub 2020 Aug 30. Bioorg Med Chem. 2020. PMID: 33007545 Free PMC article.

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