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A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike.
Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Chu HY, Neher RA, Bloom JD. Dadonaite B, et al. Among authors: ho dd. Cell. 2023 Mar 16;186(6):1263-1278.e20. doi: 10.1016/j.cell.2023.02.001. Epub 2023 Feb 13. Cell. 2023. PMID: 36868218 Free PMC article.
Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants.
Wang Q, Iketani S, Li Z, Liu L, Guo Y, Huang Y, Bowen AD, Liu M, Wang M, Yu J, Valdez R, Lauring AS, Sheng Z, Wang HH, Gordon A, Liu L, Ho DD. Wang Q, et al. Among authors: ho dd. Cell. 2023 Jan 19;186(2):279-286.e8. doi: 10.1016/j.cell.2022.12.018. Epub 2022 Dec 14. Cell. 2023. PMID: 36580913 Free PMC article.
Antibody Response to Omicron BA.4-BA.5 Bivalent Booster.
Wang Q, Bowen A, Valdez R, Gherasim C, Gordon A, Liu L, Ho DD. Wang Q, et al. Among authors: ho dd. N Engl J Med. 2023 Feb 9;388(6):567-569. doi: 10.1056/NEJMc2213907. Epub 2023 Jan 11. N Engl J Med. 2023. PMID: 36630643 Free PMC article. No abstract available.
Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking.
Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD. Liu L, et al. Among authors: ho dd. Immunity. 2023 Oct 10;56(10):2442-2455.e8. doi: 10.1016/j.immuni.2023.09.003. Epub 2023 Sep 29. Immunity. 2023. PMID: 37776849 Free PMC article.
SARS-CoV-2 neutralising antibodies after a second BA.5 bivalent booster.
Wang Q, Bowen A, Ho J, Zhang RM, Valdez R, Stoneman E, Gordon A, Liu L, Ho DD. Wang Q, et al. Among authors: ho j, ho dd. Lancet. 2023 Nov 18;402(10415):1827-1828. doi: 10.1016/S0140-6736(23)02278-X. Epub 2023 Oct 31. Lancet. 2023. PMID: 37922920 No abstract available.
451 results