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CEBPA phase separation links transcriptional activity and 3D chromatin hubs.
Christou-Kent M, Cuartero S, Garcia-Cabau C, Ruehle J, Naderi J, Erber J, Neguembor MV, Plana-Carmona M, Alcoverro-Bertran M, De Andres-Aguayo L, Klonizakis A, Julià-Vilella E, Lynch C, Serrano M, Hnisz D, Salvatella X, Graf T, Stik G. Christou-Kent M, et al. Among authors: hnisz d. Cell Rep. 2023 Aug 29;42(8):112897. doi: 10.1016/j.celrep.2023.112897. Epub 2023 Jul 29. Cell Rep. 2023. PMID: 37516962 Free article.
Corrigendum: Small genomic insertions form enhancers that misregulate oncogenes.
Abraham BJ, Hnisz D, Weintraub AS, Kwiatkowski N, Li CH, Li Z, Weichert-Leahey N, Rahman S, Liu Y, Etchin J, Li B, Shen S, Lee TI, Zhang J, Look AT, Mansour MR, Young RA. Abraham BJ, et al. Among authors: hnisz d. Nat Commun. 2017 Jun 1;8:15797. doi: 10.1038/ncomms15797. Nat Commun. 2017. PMID: 28569765 Free PMC article.
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas.
Clark VE, Harmancı AS, Bai H, Youngblood MW, Lee TI, Baranoski JF, Ercan-Sencicek AG, Abraham BJ, Weintraub AS, Hnisz D, Simon M, Krischek B, Erson-Omay EZ, Henegariu O, Carrión-Grant G, Mishra-Gorur K, Durán D, Goldmann JE, Schramm J, Goldbrunner R, Piepmeier JM, Vortmeyer AO, Günel JM, Bilgüvar K, Yasuno K, Young RA, Günel M. Clark VE, et al. Among authors: hnisz d. Nat Genet. 2016 Oct;48(10):1253-9. doi: 10.1038/ng.3651. Epub 2016 Aug 22. Nat Genet. 2016. PMID: 27548314 Free PMC article.
Selective Mediator dependence of cell-type-specifying transcription.
Jaeger MG, Schwalb B, Mackowiak SD, Velychko T, Hanzl A, Imrichova H, Brand M, Agerer B, Chorn S, Nabet B, Ferguson FM, Müller AC, Bergthaler A, Gray NS, Bradner JE, Bock C, Hnisz D, Cramer P, Winter GE. Jaeger MG, et al. Among authors: hnisz d. Nat Genet. 2020 Jul;52(7):719-727. doi: 10.1038/s41588-020-0635-0. Epub 2020 Jun 1. Nat Genet. 2020. PMID: 32483291 Free PMC article.
Aberrant phase separation and nucleolar dysfunction in rare genetic diseases.
Mensah MA, Niskanen H, Magalhaes AP, Basu S, Kircher M, Sczakiel HL, Reiter AMV, Elsner J, Meinecke P, Biskup S, Chung BHY, Dombrowsky G, Eckmann-Scholz C, Hitz MP, Hoischen A, Holterhus PM, Hülsemann W, Kahrizi K, Kalscheuer VM, Kan A, Krumbiegel M, Kurth I, Leubner J, Longardt AC, Moritz JD, Najmabadi H, Skipalova K, Snijders Blok L, Tzschach A, Wiedersberg E, Zenker M, Garcia-Cabau C, Buschow R, Salvatella X, Kraushar ML, Mundlos S, Caliebe A, Spielmann M, Horn D, Hnisz D. Mensah MA, et al. Among authors: hnisz d. Nature. 2023 Feb;614(7948):564-571. doi: 10.1038/s41586-022-05682-1. Epub 2023 Feb 8. Nature. 2023. PMID: 36755093 Free PMC article.
Rational optimization of a transcription factor activation domain inhibitor.
Basu S, Martínez-Cristóbal P, Frigolé-Vivas M, Pesarrodona M, Lewis M, Szulc E, Bañuelos CA, Sánchez-Zarzalejo C, Bielskutė S, Zhu J, Pombo-García K, Garcia-Cabau C, Zodi L, Dockx H, Smak J, Kaur H, Batlle C, Mateos B, Biesaga M, Escobedo A, Bardia L, Verdaguer X, Ruffoni A, Mawji NR, Wang J, Obst JK, Tam T, Brun-Heath I, Ventura S, Meierhofer D, García J, Robustelli P, Stracker TH, Sadar MD, Riera A, Hnisz D, Salvatella X. Basu S, et al. Among authors: hnisz d. Nat Struct Mol Biol. 2023 Dec;30(12):1958-1969. doi: 10.1038/s41594-023-01159-5. Epub 2023 Dec 4. Nat Struct Mol Biol. 2023. PMID: 38049566 Free PMC article.
Transcriptional Addiction in Cancer.
Bradner JE, Hnisz D, Young RA. Bradner JE, et al. Among authors: hnisz d. Cell. 2017 Feb 9;168(4):629-643. doi: 10.1016/j.cell.2016.12.013. Cell. 2017. PMID: 28187285 Free PMC article. Review.
A Phase Separation Model for Transcriptional Control.
Hnisz D, Shrinivas K, Young RA, Chakraborty AK, Sharp PA. Hnisz D, et al. Cell. 2017 Mar 23;169(1):13-23. doi: 10.1016/j.cell.2017.02.007. Cell. 2017. PMID: 28340338 Free PMC article. Review.
35 results