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Novel engineered nanobodies specific for N-terminal region of alpha-synuclein recognize Lewy-body pathology and inhibit in-vitro seeded aggregation and toxicity.
Hmila I, Vaikath NN, Majbour NK, Erskine D, Sudhakaran IP, Gupta V, Ghanem SS, Islam Z, Emara MM, Abdesselem HB, Kolatkar PR, Achappa DK, Vinardell T, El-Agnaf OMA. Hmila I, et al. FEBS J. 2022 Aug;289(15):4657-4673. doi: 10.1111/febs.16376. Epub 2022 Feb 25. FEBS J. 2022. PMID: 35090199 Free PMC article.
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