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Endothelial-Specific Loss of Sphingosine-1-Phosphate Receptor 1 Increases Vascular Permeability and Exacerbates Bleomycin-induced Pulmonary Fibrosis.
Knipe RS, Spinney JJ, Abe EA, Probst CK, Franklin A, Logue A, Giacona F, Drummond M, Griffith J, Brazee PL, Hariri LP, Montesi SB, Black KE, Hla T, Kuo A, Cartier A, Engelbrecht E, Christoffersen C, Shea BS, Tager AM, Medoff BD. Knipe RS, et al. Among authors: hla t. Am J Respir Cell Mol Biol. 2022 Jan;66(1):38-52. doi: 10.1165/rcmb.2020-0408OC. Am J Respir Cell Mol Biol. 2022. PMID: 34343038 Free PMC article.
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival.
Van Brocklyn JR, Lee MJ, Menzeleev R, Olivera A, Edsall L, Cuvillier O, Thomas DM, Coopman PJ, Thangada S, Liu CH, Hla T, Spiegel S. Van Brocklyn JR, et al. Among authors: hla t. J Cell Biol. 1998 Jul 13;142(1):229-40. doi: 10.1083/jcb.142.1.229. J Cell Biol. 1998. PMID: 9660876 Free PMC article.
Van Brocklyn, S. Thangada, C.H. Liu, A.R. Hand, R. Menzeleev, S. Spiegel, and T. Hla. 1998. Science. 279:1552-1555). Edg-1 binds SPP with remarkable specificity as only sphinganine-1-phosphate displaced radiolabeled SPP, while other sphingolipids did not. ...
Van Brocklyn, S. Thangada, C.H. Liu, A.R. Hand, R. Menzeleev, S. Spiegel, and T. Hla. 1998. Science. 279:1552-1555). Edg-1 bin …
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M.
Christoffersen C, Obinata H, Kumaraswamy SB, Galvani S, Ahnström J, Sevvana M, Egerer-Sieber C, Muller YA, Hla T, Nielsen LB, Dahlbäck B. Christoffersen C, et al. Among authors: hla t. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9613-8. doi: 10.1073/pnas.1103187108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606363 Free PMC article.
287 results