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Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis.
Brown EM, Ke X, Hitchcock D, Jeanfavre S, Avila-Pacheco J, Nakata T, Arthur TD, Fornelos N, Heim C, Franzosa EA, Watson N, Huttenhower C, Haiser HJ, Dillow G, Graham DB, Finlay BB, Kostic AD, Porter JA, Vlamakis H, Clish CB, Xavier RJ. Brown EM, et al. Among authors: hitchcock d. Cell Host Microbe. 2019 May 8;25(5):668-680.e7. doi: 10.1016/j.chom.2019.04.002. Cell Host Microbe. 2019. PMID: 31071294 Free PMC article.
Starved epithelial cells uptake extracellular matrix for survival.
Muranen T, Iwanicki MP, Curry NL, Hwang J, DuBois CD, Coloff JL, Hitchcock DS, Clish CB, Brugge JS, Kalaany NY. Muranen T, et al. Among authors: hitchcock ds. Nat Commun. 2017 Jan 10;8:13989. doi: 10.1038/ncomms13989. Nat Commun. 2017. PMID: 28071763 Free PMC article.
Critical role for arginase 2 in obesity-associated pancreatic cancer.
Zaytouni T, Tsai PY, Hitchcock DS, DuBois CD, Freinkman E, Lin L, Morales-Oyarvide V, Lenehan PJ, Wolpin BM, Mino-Kenudson M, Torres EM, Stylopoulos N, Clish CB, Kalaany NY. Zaytouni T, et al. Among authors: hitchcock ds. Nat Commun. 2017 Aug 14;8(1):242. doi: 10.1038/s41467-017-00331-y. Nat Commun. 2017. PMID: 28808255 Free PMC article.
Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis.
Xu H, Lee MS, Tsai PY, Adler AS, Curry NL, Challa S, Freinkman E, Hitchcock DS, Copps KD, White MF, Bronson RT, Marcotrigiano M, Wu Y, Clish CB, Kalaany NY. Xu H, et al. Among authors: hitchcock ds. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4228-4233. doi: 10.1073/pnas.1718414115. Epub 2018 Apr 2. Proc Natl Acad Sci U S A. 2018. PMID: 29610318 Free PMC article.
Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
Tsai PY, Lee MS, Jadhav U, Naqvi I, Madha S, Adler A, Mistry M, Naumenko S, Lewis CA, Hitchcock DS, Roberts FR, DelNero P, Hank T, Honselmann KC, Morales Oyarvide V, Mino-Kenudson M, Clish CB, Shivdasani RA, Kalaany NY. Tsai PY, et al. Among authors: hitchcock ds. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2003014118. doi: 10.1073/pnas.2003014118. Proc Natl Acad Sci U S A. 2021. PMID: 33653947 Free PMC article.
Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer.
Lee MS, Dennis C, Naqvi I, Dailey L, Lorzadeh A, Ye G, Zaytouni T, Adler A, Hitchcock DS, Lin L, Hoffman MT, Bhuiyan AM, Barth JL, Machacek ME, Mino-Kenudson M, Dougan SK, Jadhav U, Clish CB, Kalaany NY. Lee MS, et al. Among authors: hitchcock ds. Nature. 2023 Apr;616(7956):339-347. doi: 10.1038/s41586-023-05891-2. Epub 2023 Mar 29. Nature. 2023. PMID: 36991126 Free PMC article.
Cannulation Skill Assessment Using Functional Data Analysis.
Liu Z, Hitchcock DB, Singapogu RB. Liu Z, et al. Among authors: hitchcock db. IEEE J Biomed Health Inform. 2023 Sep;27(9):4512-4523. doi: 10.1109/JBHI.2023.3283188. Epub 2023 Sep 6. IEEE J Biomed Health Inform. 2023. PMID: 37310836
114 results