Hirschmann R - Search Results

1

Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics.

Smith AB 3rd, Charnley AK, Mesaros EF, Kikuchi O, Wang W, Benowitz A, Chu CL, Feng JJ, Chen KH, Lin A, Cheng FC, Taylor L, Hirschmann R. Smith AB 3rd, et al. Among authors: hirschmann r. Org Lett. 2005 Feb 3;7(3):399-402. doi: 10.1021/ol0476974. Org Lett. 2005. PMID: 15673249

2

Synthesis and binding affinities of novel SRIF-mimicking beta-D-glucosides satisfying the requirement for a pi-cloud at C1.

Angeles AR, Neagu I, Birzin ET, Thornton ER, Smith AB 3rd, Hirschmann R. Angeles AR, et al. Among authors: hirschmann r. Org Lett. 2005 Mar 17;7(6):1121-4. doi: 10.1021/ol050119i. Org Lett. 2005. PMID: 15760154

3

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains.

Smith AB 3rd, Charnley AK, Harada H, Beiger JJ, Cantin LD, Kenesky CS, Hirschmann R, Munshi S, Olsen DB, Stahlhut MW, Schleif WA, Kuo LC. Smith AB 3rd, et al. Among authors: hirschmann r. Bioorg Med Chem Lett. 2006 Feb 15;16(4):859-63. doi: 10.1016/j.bmcl.2005.11.011. Epub 2005 Nov 18. Bioorg Med Chem Lett. 2006. PMID: 16298527

4

Design and synthesis of potent cystine-free cyclic hexapeptide agonists at the human urotensin receptor.

Foister S, Taylor LL, Feng JJ, Chen WL, Lin A, Cheng FC, Smith AB 3rd, Hirschmann R. Foister S, et al. Among authors: hirschmann r. Org Lett. 2006 Apr 27;8(9):1799-802. doi: 10.1021/ol060278h. Org Lett. 2006. PMID: 16623554

5

Catechol: A minimal scaffold for non-peptide peptidomimetics of the i + 1 and i + 2 positions of the beta-turn of somatostatin.

Mowery BP, Prasad V, Kenesky CS, Angeles AR, Taylor LL, Feng JJ, Chen WL, Lin A, Cheng FC, Smith AB 3rd, Hirschmann R. Mowery BP, et al. Among authors: hirschmann r. Org Lett. 2006 Sep 28;8(20):4397-400. doi: 10.1021/ol061488x. Org Lett. 2006. PMID: 16986909

6

Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 1. From nonpeptide peptidomimetics to nanotubes.

Smith AB 3rd, Wang W, Charnley AK, Carroll PJ, Kenesky CS, Hirschmann R. Smith AB 3rd, et al. Among authors: hirschmann r. Org Lett. 2010 Jul 2;12(13):2990-3. doi: 10.1021/ol101007n. Org Lett. 2010. PMID: 20518540 Free PMC article.

7

Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 2. Macrocyclic hexapyrrolinones.

Smith AB 3rd, Xiong H, Charnley AK, Brenner M, Mesaros EF, Kenesky CS, Di Costanzo L, Christianson DW, Hirschmann R. Smith AB 3rd, et al. Among authors: hirschmann r. Org Lett. 2010 Jul 2;12(13):2994-7. doi: 10.1021/ol101008y. Org Lett. 2010. PMID: 20518572 Free PMC article.

8

Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge".

Smith AB 3rd, Charnley AK, Hirschmann R. Smith AB 3rd, et al. Among authors: hirschmann r. Acc Chem Res. 2011 Mar 15;44(3):180-93. doi: 10.1021/ar1001186. Epub 2010 Dec 22. Acc Chem Res. 2011. PMID: 21175156 Free PMC article.

9

Design, synthesis, and evaluation of a pyrrolinone-based matrix metalloprotease inhibitor.

Smith AB 3rd, Nittoli T, Sprengeler PA, Duan JJ, Liu RQ, Hirschmann RF. Smith AB 3rd, et al. Among authors: hirschmann rf. Org Lett. 2000 Nov 30;2(24):3809-12. doi: 10.1021/ol000254p. Org Lett. 2000. PMID: 11101425

10

A second-generation synthesis of polypyrrolinone nonpeptidomimetics: prelude to the synthesis of polypyrrolinones on solid support.

Smith AB 3rd, Liu H, Hirschmann R. Smith AB 3rd, et al. Among authors: hirschmann r. Org Lett. 2000 Jul 13;2(14):2037-40. doi: 10.1021/ol0059293. Org Lett. 2000. PMID: 10891224

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