Hirschey MD - Search Results

1

Optical imaging reveals chemotherapy-induced metabolic reprogramming of residual disease and recurrence.

Sunassee ED, Deutsch RJ, D'Agostino VW, Castellano-Escuder P, Siebeneck EA, Ilkayeva O, Crouch BT, Madonna MC, Everitt J, Alvarez JV, Palmer GM, Hirschey MD, Ramanujam N. Sunassee ED, et al. Among authors: hirschey md. Sci Adv. 2024 Apr 5;10(14):eadj7540. doi: 10.1126/sciadv.adj7540. Epub 2024 Apr 5. Sci Adv. 2024. PMID: 38579004 Free PMC article.

2

In vivo metabolic imaging identifies lipid vulnerability in a preclinical model of Her2+/Neu breast cancer residual disease and recurrence.

Madonna MC, Duer JE, McKinney BJ, Sunassee ED, Crouch BT, Ilkayeva O, Hirschey MD, Alvarez JV, Ramanujam N. Madonna MC, et al. Among authors: hirschey md. NPJ Breast Cancer. 2022 Sep 26;8(1):111. doi: 10.1038/s41523-022-00481-3. NPJ Breast Cancer. 2022. PMID: 36163365 Free PMC article.

3

In Vivo Optical Metabolic Imaging of Long-Chain Fatty Acid Uptake in Orthotopic Models of Triple-Negative Breast Cancer.

Madonna MC, Duer JE, Lee JV, Williams J, Avsaroglu B, Zhu C, Deutsch R, Wang R, Crouch BT, Hirschey MD, Goga A, Ramanujam N. Madonna MC, et al. Among authors: hirschey md. Cancers (Basel). 2021 Jan 5;13(1):148. doi: 10.3390/cancers13010148. Cancers (Basel). 2021. PMID: 33466329 Free PMC article.

4

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism.

Fox DB, Garcia NMG, McKinney BJ, Lupo R, Noteware LC, Newcomb R, Liu J, Locasale JW, Hirschey MD, Alvarez JV. Fox DB, et al. Among authors: hirschey md. Nat Metab. 2020 Apr;2(4):318-334. doi: 10.1038/s42255-020-0191-z. Epub 2020 Apr 20. Nat Metab. 2020. PMID: 32691018 Free PMC article.

5

Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition.

Peterson BS, Campbell JE, Ilkayeva O, Grimsrud PA, Hirschey MD, Newgard CB. Peterson BS, et al. Among authors: hirschey md. Cell Rep. 2018 Jul 3;24(1):209-223.e6. doi: 10.1016/j.celrep.2018.05.088. Cell Rep. 2018. PMID: 29972782 Free PMC article.

6

Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone.

Gonzalez-Hunt CP, Luz AL, Ryde IT, Turner EA, Ilkayeva OR, Bhatt DP, Hirschey MD, Meyer JN. Gonzalez-Hunt CP, et al. Among authors: hirschey md. Toxicology. 2021 Jan 15;447:152630. doi: 10.1016/j.tox.2020.152630. Epub 2020 Nov 11. Toxicology. 2021. PMID: 33188857 Free PMC article.

7

From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans.

Luz AL, Godebo TR, Bhatt DP, Ilkayeva OR, Maurer LL, Hirschey MD, Meyer JN. Luz AL, et al. Among authors: hirschey md. Toxicol Sci. 2016 Aug;152(2):349-62. doi: 10.1093/toxsci/kfw093. Epub 2016 May 20. Toxicol Sci. 2016. PMID: 27208080 Free PMC article.

8

Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation.

McDonnell E, Crown SB, Fox DB, Kitir B, Ilkayeva OR, Olsen CA, Grimsrud PA, Hirschey MD. McDonnell E, et al. Among authors: hirschey md. Cell Rep. 2016 Nov 1;17(6):1463-1472. doi: 10.1016/j.celrep.2016.10.012. Cell Rep. 2016. PMID: 27806287 Free PMC article.

9

A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.

Wagner GR, Bhatt DP, O'Connell TM, Thompson JW, Dubois LG, Backos DS, Yang H, Mitchell GA, Ilkayeva OR, Stevens RD, Grimsrud PA, Hirschey MD. Wagner GR, et al. Among authors: hirschey md. Cell Metab. 2017 Apr 4;25(4):823-837.e8. doi: 10.1016/j.cmet.2017.03.006. Cell Metab. 2017. PMID: 28380375 Free PMC article.

10

Statin therapy inhibits fatty acid synthase via dynamic protein modifications.

Trub AG, Wagner GR, Anderson KA, Crown SB, Zhang GF, Thompson JW, Ilkayeva OR, Stevens RD, Grimsrud PA, Kulkarni RA, Backos DS, Meier JL, Hirschey MD. Trub AG, et al. Among authors: hirschey md. Nat Commun. 2022 May 10;13(1):2542. doi: 10.1038/s41467-022-30060-w. Nat Commun. 2022. PMID: 35538051 Free PMC article.

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