Hirsch AKH - Search Results

1

Low-Dimensional Metal-Organic Coordination Structures on Graphene.

Li J, Solianyk L, Schmidt N, Baker B, Gottardi S, Moreno Lopez JC, Enache M, Monjas L, van der Vlag R, Havenith RWA, Hirsch AKH, Stöhr M. Li J, et al. Among authors: hirsch akh. J Phys Chem C Nanomater Interfaces. 2019 May 23;123(20):12730-12735. doi: 10.1021/acs.jpcc.9b00326. Epub 2019 Apr 30. J Phys Chem C Nanomater Interfaces. 2019. PMID: 31156737 Free PMC article.

2

Structure-based design of potent small-molecule binders to the S-component of the ECF transporter for thiamine.

Swier LJ, Monjas L, Guskov A, de Voogd AR, Erkens GB, Slotboom DJ, Hirsch AK. Swier LJ, et al. Chembiochem. 2015 Mar 23;16(5):819-26. doi: 10.1002/cbic.201402673. Epub 2015 Feb 12. Chembiochem. 2015. PMID: 25676607

3

Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS.

Masini T, Lacy B, Monjas L, Hawksley D, de Voogd AR, Illarionov B, Iqbal A, Leeper FJ, Fischer M, Kontoyianni M, Hirsch AK. Masini T, et al. Org Biomol Chem. 2015 Dec 14;13(46):11263-77. doi: 10.1039/c5ob01666e. Epub 2015 Sep 28. Org Biomol Chem. 2015. PMID: 26411373

4

Harnessing dynamic combinatorial chemistry in the search for new ligands for protein targets.

Monjas L, Hirsch AK. Monjas L, et al. Future Med Chem. 2015;7(16):2095-8. doi: 10.4155/fmc.15.146. Epub 2015 Oct 29. Future Med Chem. 2015. PMID: 26510895 No abstract available.

5

Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S-Component of the Energy-Coupling Factor Transporter for Thiamine.

Monjas L, Swier LJYM, Setyawati I, Slotboom DJ, Hirsch AKH. Monjas L, et al. Among authors: hirsch akh. ChemMedChem. 2017 Oct 20;12(20):1693-1696. doi: 10.1002/cmdc.201700440. Epub 2017 Oct 6. ChemMedChem. 2017. PMID: 28960943 Free PMC article.

6

Insight into the complete substrate-binding pocket of ThiT by chemical and genetic mutations.

Swier LJYM, Monjas L, Reeßing F, Oudshoorn RC, Aisyah, Primke T, Bakker MM, van Olst E, Ritschel T, Faustino I, Marrink SJ, Hirsch AKH, Slotboom DJ. Swier LJYM, et al. Among authors: hirsch akh. Medchemcomm. 2017 Mar 31;8(5):1121-1130. doi: 10.1039/c7md00079k. eCollection 2017 May 1. Medchemcomm. 2017. PMID: 30108823 Free PMC article.

7

Comparing the Self-Assembly of Sexiphenyl-Dicarbonitrile on Graphite and Graphene on Cu(111).

Schmidt N, Li J, Gottardi S, Moreno-Lopez JC, Enache M, Monjas L, van der Vlag R, Havenith RWA, Hirsch AKH, Stöhr M. Schmidt N, et al. Among authors: hirsch akh. Chemistry. 2019 Apr 1;25(19):5065-5070. doi: 10.1002/chem.201806312. Epub 2019 Mar 12. Chemistry. 2019. PMID: 30657213 Free PMC article.

8

Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity.

Guo H, Verhoek IC, Prins GGH, van der Vlag R, van der Wouden PE, van Merkerk R, Quax WJ, Olinga P, Hirsch AKH, Dekker FJ. Guo H, et al. Among authors: hirsch akh. J Med Chem. 2019 May 9;62(9):4624-4637. doi: 10.1021/acs.jmedchem.9b00212. Epub 2019 Apr 19. J Med Chem. 2019. PMID: 30964295 Free PMC article.

9

A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1.

van der Vlag R, Guo H, Hapko U, Eleftheriadis N, Monjas L, Dekker FJ, Hirsch AKH. van der Vlag R, et al. Among authors: hirsch akh. Eur J Med Chem. 2019 Jul 15;174:45-55. doi: 10.1016/j.ejmech.2019.04.021. Epub 2019 Apr 12. Eur J Med Chem. 2019. PMID: 31026746

10

Replacement of an Indole Scaffold Targeting Human 15-Lipoxygenase-1 Using Combinatorial Chemistry.

Prismawan D, van der Vlag R, Guo H, Dekker FJ, Hirsch AKH. Prismawan D, et al. Among authors: hirsch akh. Helv Chim Acta. 2019 May;102(5):e1900040. doi: 10.1002/hlca.201900040. Epub 2019 May 2. Helv Chim Acta. 2019. PMID: 31231138 Free PMC article.

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