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A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis.
Hitomi Y, Ueno K, Aiba Y, Nishida N, Kono M, Sugihara M, Kawai Y, Kawashima M, Khor SS, Sugi K, Kouno H, Kouno H, Naganuma A, Iwamoto S, Katsushima S, Furuta K, Nikami T, Mannami T, Yamashita T, Ario K, Komatsu T, Makita F, Shimada M, Hirashima N, Yokohama S, Nishimura H, Sugimoto R, Komura T, Ota H, Kojima M, Nakamuta M, Fujimori N, Yoshizawa K, Mano Y, Takahashi H, Hirooka K, Tsuruta S, Sato T, Yamasaki K, Kugiyama Y, Motoyoshi Y, Suehiro T, Saeki A, Matsumoto K, Nagaoka S, Abiru S, Yatsuhashi H, Ito M, Kawata K, Takaki A, Arai K, Arinaga T, Abe M, Harada M, Taniai M, Zeniya M, Ohira H, Shimoda S, Komori A, Tanaka A, Ishigaki K, Nagasaki M, Tokunaga K, Nakamura M. Hitomi Y, et al. Among authors: hirooka k. Hepatology. 2024 Apr 23. doi: 10.1097/HEP.0000000000000894. Online ahead of print. Hepatology. 2024. PMID: 38652555
Potentially compromised systemic and local lactate metabolic balance in glaucoma, which could increase retinal glucose and glutamate concentrations.
Arai-Okuda M, Murai Y, Maeda H, Kanamori A, Miki T, Naito T, Sugihara K, Kono M, Tanito M, Onoe H, Hirooka K, Kiuchi Y, Shinohara M, Kusuhara S, Mori S, Ueda K, Sakamoto M, Yamada-Nakanishi Y, Nakamura M. Arai-Okuda M, et al. Among authors: hirooka k. Sci Rep. 2024 Feb 14;14(1):3683. doi: 10.1038/s41598-024-54383-4. Sci Rep. 2024. PMID: 38355836 Free PMC article.
The WATCH-DM risk score estimates clinical outcomes in type 2 diabetic patients with heart failure with preserved ejection fraction.
Iwakura K, Onishi T, Okamura A, Koyama Y, Tanaka N, Okada M, Fujii K, Seo M, Yamada T, Yano M, Hayashi T, Yasumura Y, Nakagawa Y, Tamaki S, Nakagawa A, Sotomi Y, Hikoso S, Nakatani D, Sakata Y; PURSUIT-HFpEF Investigators. Iwakura K, et al. Sci Rep. 2024 Jan 19;14(1):1746. doi: 10.1038/s41598-024-52101-8. Sci Rep. 2024. PMID: 38243047 Free PMC article.
400 results