Hirner H - Search Results

1

Kinases as targets in the treatment of solid tumors.

Giamas G, Man YL, Hirner H, Bischof J, Kramer K, Khan K, Ahmed SS, Stebbing J, Knippschild U. Giamas G, et al. Among authors: hirner h. Cell Signal. 2010 Jul;22(7):984-1002. doi: 10.1016/j.cellsig.2010.01.011. Epub 2010 Jan 21. Cell Signal. 2010. PMID: 20096351 Review.

2

Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo.

Brockschmidt C, Hirner H, Huber N, Eismann T, Hillenbrand A, Giamas G, Radunsky B, Ammerpohl O, Bohm B, Henne-Bruns D, Kalthoff H, Leithäuser F, Trauzold A, Knippschild U. Brockschmidt C, et al. Among authors: hirner h. Gut. 2008 Jun;57(6):799-806. doi: 10.1136/gut.2007.123695. Epub 2008 Jan 18. Gut. 2008. PMID: 18203806

3

Phosphorylation of CK1delta: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivo.

Giamas G, Hirner H, Shoshiashvili L, Grothey A, Gessert S, Kühl M, Henne-Bruns D, Vorgias CE, Knippschild U. Giamas G, et al. Among authors: hirner h. Biochem J. 2007 Sep 15;406(3):389-98. doi: 10.1042/BJ20070091. Biochem J. 2007. PMID: 17594292 Free PMC article.

4

Immunohistochemical characterisation of cell-type specific expression of CK1delta in various tissues of young adult BALB/c mice.

Löhler J, Hirner H, Schmidt B, Kramer K, Fischer D, Thal DR, Leithäuser F, Knippschild U. Löhler J, et al. Among authors: hirner h. PLoS One. 2009;4(1):e4174. doi: 10.1371/journal.pone.0004174. Epub 2009 Jan 12. PLoS One. 2009. PMID: 19137063 Free PMC article.

5

Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.

Hirner H, Günes C, Bischof J, Wolff S, Grothey A, Kühl M, Oswald F, Wegwitz F, Bösl MR, Trauzold A, Henne-Bruns D, Peifer C, Leithäuser F, Deppert W, Knippschild U. Hirner H, et al. PLoS One. 2012;7(1):e29709. doi: 10.1371/journal.pone.0029709. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235331 Free PMC article.

6

3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.

Peifer C, Abadleh M, Bischof J, Hauser D, Schattel V, Hirner H, Knippschild U, Laufer S. Peifer C, et al. Among authors: hirner h. J Med Chem. 2009 Dec 10;52(23):7618-30. doi: 10.1021/jm9005127. J Med Chem. 2009. PMID: 19591487

7

Analysis of cell type-specific expression of CK1 epsilon in various tissues of young adult BALB/c Mice and in mammary tumors of SV40 T-Ag-transgenic mice.

Utz AC, Hirner H, Blatz A, Hillenbrand A, Schmidt B, Deppert W, Henne-Bruns D, Fischer D, Thal DR, Leithäuser F, Knippschild U. Utz AC, et al. Among authors: hirner h. J Histochem Cytochem. 2010 Jan;58(1):1-15. doi: 10.1369/jhc.2009.954628. Epub 2009 Sep 15. J Histochem Cytochem. 2010. PMID: 19755715 Free PMC article.

8

Correction: Phosphorylation of CK1δ: identification of Ser³⁷⁰ as the major phosphorylation site targeted by PKA in vitro and in vivo.

Giamas G, Hirner H, Shoshiashvili L, Grothey A, Gessert S, Kühl M, Henne-Bruns D, Vorgias CE, Knippschild U. Giamas G, et al. Among authors: hirner h. Biochem J. 2019 Apr 18;476(8):1221-1225. doi: 10.1042/BJ-2007-0091_COR. Biochem J. 2019. PMID: 31000625 No abstract available.

9

Stem cell-like side populations in esophageal cancer: a source of chemotherapy resistance and metastases.

Zhao Y, Bao Q, Schwarz B, Zhao L, Mysliwietz J, Ellwart J, Renner A, Hirner H, Niess H, Camaj P, Angele M, Gros S, Izbicki J, Jauch KW, Nelson PJ, Bruns CJ. Zhao Y, et al. Among authors: hirner h. Stem Cells Dev. 2014 Jan 15;23(2):180-92. doi: 10.1089/scd.2013.0103. Epub 2013 Nov 13. Stem Cells Dev. 2014. PMID: 24021093

10

Regorafenib effects on human colon carcinoma xenografts monitored by dynamic contrast-enhanced computed tomography with immunohistochemical validation.

Cyran CC, Kazmierczak PM, Hirner H, Moser M, Ingrisch M, Havla L, Michels A, Eschbach R, Schwarz B, Reiser MF, Bruns CJ, Nikolaou K. Cyran CC, et al. Among authors: hirner h. PLoS One. 2013 Sep 30;8(9):e76009. doi: 10.1371/journal.pone.0076009. eCollection 2013. PLoS One. 2013. PMID: 24098755 Free PMC article.

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