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Hydroxylated benzo[c]phenanthrene metabolites cause osteoblast apoptosis and skeletal abnormalities in fish.
Suzuki N, Honda M, Sato M, Yoshitake S, Kawabe K, Tabuchi Y, Omote T, Sekiguchi T, Furusawa Y, Toriba A, Tang N, Shimasaki Y, Nagato EG, Zhang L, Srivastav AK, Amornsakun T, Kitani Y, Matsubara H, Yazawa T, Hirayama J, Hattori A, Oshima Y, Hayakawa K. Suzuki N, et al. Among authors: hirayama j. Ecotoxicol Environ Saf. 2022 Apr 1;234:113401. doi: 10.1016/j.ecoenv.2022.113401. Epub 2022 Mar 14. Ecotoxicol Environ Saf. 2022. PMID: 35298967 Free article.
De novo transcriptome analysis and gene expression profiling of fish scales isolated from Carassius auratus during space flight: Impact of melatonin on gene expression in response to space radiation.
Furusawa Y, Yamamoto T, Hattori A, Suzuki N, Hirayama J, Sekiguchi T, Tabuchi Y. Furusawa Y, et al. Among authors: hirayama j. Mol Med Rep. 2020 Oct;22(4):2627-2636. doi: 10.3892/mmr.2020.11363. Epub 2020 Jul 28. Mol Med Rep. 2020. PMID: 32945420 Free PMC article.
Oral administration of melatonin contained in drinking water increased bone strength in naturally aged mice.
Igarashi-Migitaka J, Seki A, Ikegame M, Honda M, Sekiguchi T, Mishima H, Shimizu N, Matsubara H, Srivastav AK, Hirayama J, Maruyama Y, Kamijo-Ikemori A, Hirata K, Hattori A, Suzuki N. Igarashi-Migitaka J, et al. Among authors: hirayama j. Acta Histochem. 2020 Sep;122(6):151596. doi: 10.1016/j.acthis.2020.151596. Epub 2020 Jul 18. Acta Histochem. 2020. PMID: 32778234
Physiological consequences of space flight, including abnormal bone metabolism, space radiation injury, and circadian clock dysregulation: Implications of melatonin use and regulation as a countermeasure.
Hirayama J, Hattori A, Takahashi A, Furusawa Y, Tabuchi Y, Shibata M, Nagamatsu A, Yano S, Maruyama Y, Matsubara H, Sekiguchi T, Suzuki N. Hirayama J, et al. J Pineal Res. 2023 Jan;74(1):e12834. doi: 10.1111/jpi.12834. Epub 2022 Oct 17. J Pineal Res. 2023. PMID: 36203395 Review.
Melatonin is a potential drug for the prevention of bone loss during space flight.
Ikegame M, Hattori A, Tabata MJ, Kitamura KI, Tabuchi Y, Furusawa Y, Maruyama Y, Yamamoto T, Sekiguchi T, Matsuoka R, Hanmoto T, Ikari T, Endo M, Omori K, Nakano M, Yashima S, Ejiri S, Taya T, Nakashima H, Shimizu N, Nakamura M, Kondo T, Hayakawa K, Takasaki I, Kaminishi A, Akatsuka R, Sasayama Y, Nishiuchi T, Nara M, Iseki H, Chowdhury VS, Wada S, Ijiri K, Takeuchi T, Suzuki T, Ando H, Matsuda K, Somei M, Mishima H, Mikuni-Takagaki Y, Funahashi H, Takahashi A, Watanabe Y, Maeda M, Uchida H, Hayashi A, Kambegawa A, Seki A, Yano S, Shimazu T, Suzuki H, Hirayama J, Suzuki N. Ikegame M, et al. Among authors: hirayama j. J Pineal Res. 2019 Oct;67(3):e12594. doi: 10.1111/jpi.12594. Epub 2019 Jul 19. J Pineal Res. 2019. PMID: 31286565 Free PMC article.
226 results