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Coformulation of a Novel Human α-Galactosidase A With the Pharmacological Chaperone AT1001 Leads to Improved Substrate Reduction in Fabry Mice.
Xu S, Lun Y, Brignol N, Hamler R, Schilling A, Frascella M, Sullivan S, Boyd RE, Chang K, Soska R, Garcia A, Feng J, Yasukawa H, Shardlow C, Churchill A, Ketkar A, Robertson N, Miyamoto M, Mihara K, Benjamin ER, Lockhart DJ, Hirato T, Fowles S, Valenzano KJ, Khanna R. Xu S, et al. Among authors: hirato t. Mol Ther. 2015 Jul;23(7):1169-1181. doi: 10.1038/mt.2015.87. Epub 2015 Apr 27. Mol Ther. 2015. PMID: 25915924 Free PMC article.
A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II.
Sonoda H, Morimoto H, Yoden E, Koshimura Y, Kinoshita M, Golovina G, Takagi H, Yamamoto R, Minami K, Mizoguchi A, Tachibana K, Hirato T, Takahashi K. Sonoda H, et al. Among authors: hirato t. Mol Ther. 2018 May 2;26(5):1366-1374. doi: 10.1016/j.ymthe.2018.02.032. Epub 2018 Mar 6. Mol Ther. 2018. PMID: 29606503 Free PMC article.
Physicochemical and biological evaluation of JR-131 as a biosimilar to a long-acting erythropoiesis-stimulating agent darbepoetin alfa.
Tani J, Ito Y, Tatemichi S, Yamakami M, Fukui T, Hatano Y, Kakimoto S, Kotani A, Sugimura A, Mihara K, Yamamoto R, Tanaka N, Minami K, Takahashi K, Hirato T. Tani J, et al. Among authors: hirato t. PLoS One. 2020 Apr 17;15(4):e0231830. doi: 10.1371/journal.pone.0231830. eCollection 2020. PLoS One. 2020. PMID: 32302352 Free PMC article.
Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II.
Yamamoto R, Yoden E, Tanaka N, Kinoshita M, Imakiire A, Hirato T, Minami K. Yamamoto R, et al. Among authors: hirato t. Mol Genet Metab Rep. 2021 Apr 18;27:100758. doi: 10.1016/j.ymgmr.2021.100758. eCollection 2021 Jun. Mol Genet Metab Rep. 2021. PMID: 33981582 Free PMC article.
Pharmacokinetics and pharmacodynamics of once-weekly administration of JR-142, a long-acting albumin-fused human growth hormone: A rondemized, placebo-controlled phase 1 study.
Owada Y, Okazaki M, Ikeda T, Yamamoto R, Minami K, Takahashi K, Hirato T, Mita Y, Yamamoto T, Tanizawa K, Sonoda H, Sato Y. Owada Y, et al. Among authors: hirato t. Growth Horm IGF Res. 2022 Dec;67:101500. doi: 10.1016/j.ghir.2022.101500. Epub 2022 Sep 8. Growth Horm IGF Res. 2022. PMID: 36113378 Free article. Clinical Trial.
31 results