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MNX1-HNF1B Axis Is Indispensable for Intraductal Papillary Mucinous Neoplasm Lineages.
Kato H, Tateishi K, Fujiwara H, Nakatsuka T, Yamamoto K, Kudo Y, Hayakawa Y, Nakagawa H, Tanaka Y, Ijichi H, Otsuka M, Iwadate D, Oyama H, Kanai S, Noguchi K, Suzuki T, Sato T, Hakuta R, Ishigaki K, Saito K, Saito T, Takahara N, Kishikawa T, Hamada T, Takahashi R, Miyabayashi K, Mizuno S, Kogure H, Nakai Y, Hirata Y, Toyoda A, Ichikawa K, Qu W, Morishita S, Arita J, Tanaka M, Ushiku T, Hasegawa K, Fujishiro M, Koike K. Kato H, et al. Among authors: hirata y. Gastroenterology. 2022 Apr;162(4):1272-1287.e16. doi: 10.1053/j.gastro.2021.12.254. Epub 2021 Dec 22. Gastroenterology. 2022. PMID: 34953915
BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice.
Hayakawa Y, Tsuboi M, Asfaha S, Kinoshita H, Niikura R, Konishi M, Hata M, Oya Y, Kim W, Middelhoff M, Hikiba Y, Higashijima N, Ihara S, Ushiku T, Fukayama M, Tailor Y, Hirata Y, Guha C, Yan KS, Koike K, Wang TC. Hayakawa Y, et al. Among authors: hirata y. Gastroenterology. 2019 Mar;156(4):1066-1081.e16. doi: 10.1053/j.gastro.2018.11.024. Epub 2018 Nov 15. Gastroenterology. 2019. PMID: 30448068 Free PMC article.
Deletion of Histone Methyltransferase G9a Suppresses Mutant Kras-driven Pancreatic Carcinogenesis.
Kato H, Tateishi K, Fujiwara H, Ijichi H, Yamamoto K, Nakatsuka T, Kakiuchi M, Sano M, Kudo Y, Hayakawa Y, Nakagawa H, Tanaka Y, Otsuka M, Hirata Y, Tachibana M, Shinkai Y, Koike K. Kato H, et al. Among authors: hirata y. Cancer Genomics Proteomics. 2020 Nov-Dec;17(6):695-705. doi: 10.21873/cgp.20224. Cancer Genomics Proteomics. 2020. PMID: 33099471 Free PMC article.
Axin2+ Peribiliary Glands in the Periampullary Region Generate Biliary Epithelial Stem Cells That Give Rise to Ampullary Carcinoma.
Hayata Y, Nakagawa H, Kurosaki S, Kawamura S, Matsushita Y, Hayakawa Y, Suzuki N, Hata M, Tsuboi M, Kinoshita H, Miyabayashi K, Mizutani H, Nakagomi R, Ikenoue T, Hirata Y, Arita J, Hasegawa K, Tateishi K, Koike K. Hayata Y, et al. Among authors: hirata y. Gastroenterology. 2021 May;160(6):2133-2148.e6. doi: 10.1053/j.gastro.2021.01.028. Epub 2021 Jan 16. Gastroenterology. 2021. PMID: 33465373 Free article.
Impact of histone demethylase KDM3A-dependent AP-1 transactivity on hepatotumorigenesis induced by PI3K activation.
Nakatsuka T, Tateishi K, Kudo Y, Yamamoto K, Nakagawa H, Fujiwara H, Takahashi R, Miyabayashi K, Asaoka Y, Tanaka Y, Ijichi H, Hirata Y, Otsuka M, Kato M, Sakai J, Tachibana M, Aburatani H, Shinkai Y, Koike K. Nakatsuka T, et al. Among authors: hirata y. Oncogene. 2017 Nov 9;36(45):6262-6271. doi: 10.1038/onc.2017.222. Epub 2017 Jul 10. Oncogene. 2017. PMID: 28692045
Apoptosis signal-regulating kinase 1 regulates colitis and colitis-associated tumorigenesis by the innate immune responses.
Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Otsuka M, Ijichi H, Ikenoue T, Tateishi K, Akanuma M, Ogura K, Yoshida H, Ichijo H, Omata M, Maeda S. Hayakawa Y, et al. Among authors: hirata y. Gastroenterology. 2010 Mar;138(3):1055-67.e1-4. doi: 10.1053/j.gastro.2009.11.015. Epub 2009 Nov 18. Gastroenterology. 2010. PMID: 19931259
Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.
Takahashi R, Hirata Y, Sakitani K, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Sakamoto K, Hikiba Y, Ijichi H, Moses HL, Maeda S, Koike K. Takahashi R, et al. Among authors: hirata y. Cancer Sci. 2013 Mar;104(3):337-44. doi: 10.1111/cas.12080. Epub 2013 Jan 24. Cancer Sci. 2013. PMID: 23237571 Free PMC article.
Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells.
Yamamoto S, Tateishi K, Kudo Y, Yamamoto K, Isagawa T, Nagae G, Nakatsuka T, Asaoka Y, Ijichi H, Hirata Y, Otsuka M, Ikenoue T, Aburatani H, Omata M, Koike K. Yamamoto S, et al. Among authors: hirata y. Carcinogenesis. 2013 Oct;34(10):2380-8. doi: 10.1093/carcin/bgt174. Epub 2013 May 22. Carcinogenesis. 2013. PMID: 23698634
Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.
Yamamoto K, Tateishi K, Kudo Y, Sato T, Yamamoto S, Miyabayashi K, Matsusaka K, Asaoka Y, Ijichi H, Hirata Y, Otsuka M, Nakai Y, Isayama H, Ikenoue T, Kurokawa M, Fukayama M, Kokudo N, Omata M, Koike K. Yamamoto K, et al. Among authors: hirata y. Carcinogenesis. 2014 Nov;35(11):2404-14. doi: 10.1093/carcin/bgu136. Epub 2014 Jun 19. Carcinogenesis. 2014. PMID: 24947179
3,129 results