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Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N. Nomura M, et al. Among authors: hirao a. Nat Commun. 2023 Dec 13;14(1):8095. doi: 10.1038/s41467-023-43630-3. Nat Commun. 2023. PMID: 38092728 Free PMC article.
Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples.
Ueno M, Tomita T, Arakawa H, Kakuta T, Yamagishi TA, Terakawa J, Daikoku T, Horike SI, Si S, Kurayoshi K, Ito C, Kasahara A, Tadokoro Y, Kobayashi M, Fukuwatari T, Tamai I, Hirao A, Ogoshi T. Ueno M, et al. Among authors: hirao a. Commun Chem. 2020 Dec 7;3(1):183. doi: 10.1038/s42004-020-00430-w. Commun Chem. 2020. PMID: 36703437 Free PMC article.
Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation.
Kurayoshi K, Takase Y, Ueno M, Ohta K, Fuse K, Ikeda S, Watanabe T, Nishida Y, Horike SI, Hosomichi K, Ishikawa Y, Tadokoro Y, Kobayashi M, Kasahara A, Jing Y, Shoulkamy MI, Meguro-Horike M, Kojima K, Kiyoi H, Sugiyama H, Nagase H, Tajima A, Hirao A. Kurayoshi K, et al. Among authors: hirao a. Cell Death Dis. 2023 Sep 29;14(9):642. doi: 10.1038/s41419-023-06168-2. Cell Death Dis. 2023. PMID: 37773170 Free PMC article.
279 results