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Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial.
Shoamanesh A, Mundl H, Smith EE, Masjuan J, Milanov I, Hirano T, Agafina A, Campbell B, Caso V, Mas JL, Dong Q, Turcani P, Christensen H, Ferro JM, Veltkamp R, Mikulik R, De Marchis GM, Robinson T, Lemmens R, Stepien A, Greisenegger S, Roine R, Csiba L, Khatri P, Coutinho J, Lindgren AG, Demchuk AM, Colorado P, Kirsch B, Neumann C, Heenan L, Xu L, Connolly SJ, Hart RG; PACIFIC-Stroke Investigators. Shoamanesh A, et al. Among authors: hirano t. Lancet. 2022 Sep 24;400(10357):997-1007. doi: 10.1016/S0140-6736(22)01588-4. Epub 2022 Sep 2. Lancet. 2022. PMID: 36063821 Clinical Trial.
Oral Anticoagulants in the Oldest Old with Recent Stroke and Atrial Fibrillation.
Polymeris AA, Macha K, Paciaroni M, Wilson D, Koga M, Cappellari M, Schaedelin S, Zietz A, Peters N, Seiffge DJ, Haupenthal D, Gassmann L, De Marchis GM, Wang R, Gensicke H, Stoll S, Thilemann S, Avramiotis NS, Bonetti B, Tsivgoulis G, Ambler G, Alberti A, Yoshimura S, Brown MM, Shiozawa M, Lip GYH, Venti M, Acciarresi M, Tanaka K, Mosconi MG, Takagi M, Jäger RH, Muir K, Inoue M, Schwab S, Bonati LH, Lyrer PA, Toyoda K, Caso V, Werring DJ, Kallmünzer B, Engelter ST; NOACISP-LONGTERM, Erlangen Registry, CROMIS-2, RAF, RAF-DOAC, SAMURAI-NVAF and Verona Registry Collaborators. Polymeris AA, et al. Ann Neurol. 2022 Jan;91(1):78-88. doi: 10.1002/ana.26267. Epub 2021 Nov 29. Ann Neurol. 2022. PMID: 34747514 Free PMC article.
Practical "1-2-3-4-Day" Rule for Starting Direct Oral Anticoagulants After Ischemic Stroke With Atrial Fibrillation: Combined Hospital-Based Cohort Study.
Kimura S, Toyoda K, Yoshimura S, Minematsu K, Yasaka M, Paciaroni M, Werring DJ, Yamagami H, Nagao T, Yoshimura S, Polymeris A, Zietz A, Engelter ST, Kallmünzer B, Cappellari M, Chiba T, Yoshimoto T, Shiozawa M, Kitazono T, Koga M; SAMURAI, RELAXED, RAF, RAF-NOAC, CROMIS-2, NOACISP LONGTERM, Erlangen Registry and Verona Registry Investigators. Kimura S, et al. Stroke. 2022 May;53(5):1540-1549. doi: 10.1161/STROKEAHA.121.036695. Epub 2022 Feb 2. Stroke. 2022. PMID: 35105180 Free PMC article.
Effect of the Factor XIa Inhibitor Asundexian According to Baseline Infarct Pattern and on MRI Covert Infarct Outcomes.
Smith EE, Shoamanesh A, Xu L, Heenan L, Saad F, Colorado P, Chen CH, Lemmens R, De Marchis GM, Caso V, Masjuan J, Hirano T, Milanov I, Campbell BCV, Mas JL, Connolly SJ, Mundl H, Hart RG; PACIFIC-Stroke Steering Committee and Investigators. Smith EE, et al. Among authors: hirano t. Stroke. 2024 Feb;55(2):392-402. doi: 10.1161/STROKEAHA.123.043198. Epub 2024 Jan 4. Stroke. 2024. PMID: 38174569 Clinical Trial.
Design and Rationale of the RELAXED (Recurrent Embolism Lessened by rivaroxaban, an Anti-Xa agent, of Early Dosing for acute ischemic stroke and transient ischemic attack with atrial fibrillation) Study.
Yasaka M, Minematsu K, Toyoda K, Yamagami H, Yoshimura S, Nagao T, Mori E, Hirano T, Hamasaki T, Yamaguchi T. Yasaka M, et al. Among authors: hirano t. J Stroke Cerebrovasc Dis. 2016 Jun;25(6):1342-8. doi: 10.1016/j.jstrokecerebrovasdis.2016.01.035. Epub 2016 Mar 14. J Stroke Cerebrovasc Dis. 2016. PMID: 26987488
Subcutaneous Heparin Therapy for Patients with Cancer-Associated Stroke.
Kawano H, Honda Y, Amano T, Okano H, Suzuki R, Torii M, Unno Y, Shiokawa Y, Hirano T. Kawano H, et al. Among authors: hirano t. J Stroke Cerebrovasc Dis. 2019 Feb;28(2):399-404. doi: 10.1016/j.jstrokecerebrovasdis.2018.10.012. Epub 2018 Nov 5. J Stroke Cerebrovasc Dis. 2019. PMID: 30409745
Rivaroxaban administration after acute ischemic stroke: The RELAXED study.
Yasaka M, Minematsu K, Toyoda K, Mori E, Hirano T, Hamasaki T, Yamagami H, Nagao T, Yoshimura S, Uchiyama S; RELAXED study group. Yasaka M, et al. Among authors: hirano t. PLoS One. 2019 Feb 13;14(2):e0212354. doi: 10.1371/journal.pone.0212354. eCollection 2019. PLoS One. 2019. PMID: 30759158 Free PMC article.
Sex Differences in Management and Outcomes of Cardioembolic Stroke: Post HOC Analyses of the RELAXED Study.
Okada T, Uchida K, Sakakibara F, Kageyama H, Yasaka M, Toyoda K, Mori E, Hirano T, Hamasaki T, Yamagami H, Nagao T, Uchiyama S, Minematsu K, Yoshimura S; RELAXED study group. Okada T, et al. Among authors: hirano t. J Stroke Cerebrovasc Dis. 2021 Apr;30(4):105613. doi: 10.1016/j.jstrokecerebrovasdis.2021.105613. Epub 2021 Jan 30. J Stroke Cerebrovasc Dis. 2021. PMID: 33529924
4,197 results