Hirano N - Search Results

1

Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy.

Boukhaled GM, Gadalla R, Elsaesser HJ, Abd-Rabbo D, Quevedo R, Yang SYC, Guo M, Wang BX, Noamani B, Gray D, Lau SCM, Taylor K, Aung K, Spreafico A, Hansen AR, Saibil SD, Hirano N, Guidos C, Pugh TJ, McGaha TL, Ohashi PS, Sacher AG, Butler MO, Brooks DG. Boukhaled GM, et al. Among authors: hirano n. Nat Immunol. 2022 Aug;23(8):1273-1283. doi: 10.1038/s41590-022-01262-7. Epub 2022 Jul 14. Nat Immunol. 2022. PMID: 35835962

2

Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application.

von Bergwelt-Baildon MS, Vonderheide RH, Maecker B, Hirano N, Anderson KS, Butler MO, Xia Z, Zeng WY, Wucherpfennig KW, Nadler LM, Schultze JL. von Bergwelt-Baildon MS, et al. Among authors: hirano n. Blood. 2002 May 1;99(9):3319-25. doi: 10.1182/blood.v99.9.3319. Blood. 2002. PMID: 11964299 Free article.

3

Efficient presentation of naturally processed HLA class I peptides by artificial antigen-presenting cells for the generation of effective antitumor responses.

Hirano N, Butler MO, Xia Z, Berezovskaya A, Murray AP, Ansén S, Nadler LM. Hirano N, et al. Clin Cancer Res. 2006 May 15;12(10):2967-75. doi: 10.1158/1078-0432.CCR-05-2791. Clin Cancer Res. 2006. PMID: 16707591

4

Identification of an immunogenic CD8+ T-cell epitope derived from gamma-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia.

Hirano N, Butler MO, Xia Z, Berezovskaya A, Murray AP, Ansén S, Kojima S, Nadler LM. Hirano N, et al. Blood. 2006 Oct 15;108(8):2662-8. doi: 10.1182/blood-2006-04-017566. Epub 2006 Jun 15. Blood. 2006. PMID: 16778141 Free PMC article.

5

Long-lived antitumor CD8+ lymphocytes for adoptive therapy generated using an artificial antigen-presenting cell.

Butler MO, Lee JS, Ansén S, Neuberg D, Hodi FS, Murray AP, Drury L, Berezovskaya A, Mulligan RC, Nadler LM, Hirano N. Butler MO, et al. Among authors: hirano n. Clin Cancer Res. 2007 Mar 15;13(6):1857-67. doi: 10.1158/1078-0432.CCR-06-1905. Clin Cancer Res. 2007. PMID: 17363542

6

Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21.

Ansén S, Butler MO, Berezovskaya A, Murray AP, Stevenson K, Nadler LM, Hirano N. Ansén S, et al. Among authors: hirano n. Clin Cancer Res. 2008 Oct 1;14(19):6125-36. doi: 10.1158/1078-0432.CCR-08-1146. Clin Cancer Res. 2008. PMID: 18829491 Free PMC article.

7

A panel of human cell-based artificial APC enables the expansion of long-lived antigen-specific CD4+ T cells restricted by prevalent HLA-DR alleles.

Butler MO, Ansén S, Tanaka M, Imataki O, Berezovskaya A, Mooney MM, Metzler G, Milstein MI, Nadler LM, Hirano N. Butler MO, et al. Among authors: hirano n. Int Immunol. 2010 Nov;22(11):863-73. doi: 10.1093/intimm/dxq440. Epub 2010 Nov 8. Int Immunol. 2010. PMID: 21059769 Free PMC article.

8

Induction of HLA-DP4-restricted anti-survivin Th1 and Th2 responses using an artificial antigen-presenting cell.

Tanaka M, Butler MO, Ansén S, Imataki O, Berezovskaya A, Nadler LM, Hirano N. Tanaka M, et al. Among authors: hirano n. Clin Cancer Res. 2011 Aug 15;17(16):5392-401. doi: 10.1158/1078-0432.CCR-10-3083. Epub 2011 Jun 24. Clin Cancer Res. 2011. PMID: 21705450 Free PMC article.

9

IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cells.

Imataki O, Ansén S, Tanaka M, Butler MO, Berezovskaya A, Milstein MI, Kuzushima K, Nadler LM, Hirano N. Imataki O, et al. Among authors: hirano n. J Immunol. 2012 Feb 15;188(4):1609-19. doi: 10.4049/jimmunol.1003446. Epub 2012 Jan 11. J Immunol. 2012. PMID: 22238455 Free PMC article.

10

Ex vivo expansion of human CD8+ T cells using autologous CD4+ T cell help.

Butler MO, Imataki O, Yamashita Y, Tanaka M, Ansén S, Berezovskaya A, Metzler G, Milstein MI, Mooney MM, Murray AP, Mano H, Nadler LM, Hirano N. Butler MO, et al. Among authors: hirano n. PLoS One. 2012;7(1):e30229. doi: 10.1371/journal.pone.0030229. Epub 2012 Jan 12. PLoS One. 2012. PMID: 22279573 Free PMC article.

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