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Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.
Nagai Y, Miyakawa N, Takuwa H, Hori Y, Oyama K, Ji B, Takahashi M, Huang XP, Slocum ST, DiBerto JF, Xiong Y, Urushihata T, Hirabayashi T, Fujimoto A, Mimura K, English JG, Liu J, Inoue KI, Kumata K, Seki C, Ono M, Shimojo M, Zhang MR, Tomita Y, Nakahara J, Suhara T, Takada M, Higuchi M, Jin J, Roth BL, Minamimoto T. Nagai Y, et al. Among authors: hirabayashi t. Nat Neurosci. 2020 Sep;23(9):1157-1167. doi: 10.1038/s41593-020-0661-3. Epub 2020 Jul 6. Nat Neurosci. 2020. PMID: 32632286
PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation.
Nagai Y, Kikuchi E, Lerchner W, Inoue KI, Ji B, Eldridge MA, Kaneko H, Kimura Y, Oh-Nishi A, Hori Y, Kato Y, Hirabayashi T, Fujimoto A, Kumata K, Zhang MR, Aoki I, Suhara T, Higuchi M, Takada M, Richmond BJ, Minamimoto T. Nagai Y, et al. Among authors: hirabayashi t. Nat Commun. 2016 Dec 6;7:13605. doi: 10.1038/ncomms13605. Nat Commun. 2016. PMID: 27922009 Free PMC article.
Chemogenetic activation of nigrostriatal dopamine neurons in freely moving common marmosets.
Mimura K, Nagai Y, Inoue KI, Matsumoto J, Hori Y, Sato C, Kimura K, Okauchi T, Hirabayashi T, Nishijo H, Yahata N, Takada M, Suhara T, Higuchi M, Minamimoto T. Mimura K, et al. Among authors: hirabayashi t. iScience. 2021 Aug 30;24(9):103066. doi: 10.1016/j.isci.2021.103066. eCollection 2021 Sep 24. iScience. 2021. PMID: 34568790 Free PMC article.
Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action.
Oyama K, Hori Y, Mimura K, Nagai Y, Eldridge MAG, Saunders RC, Miyakawa N, Hirabayashi T, Hori Y, Inoue KI, Suhara T, Takada M, Higuchi M, Richmond BJ, Minamimoto T. Oyama K, et al. Among authors: hirabayashi t. J Neurosci. 2022 Aug 10;42(32):6267-6275. doi: 10.1523/JNEUROSCI.0229-22.2022. Epub 2022 Jul 6. J Neurosci. 2022. PMID: 35794012 Free PMC article.
Chemogenetic attenuation of cortical seizures in nonhuman primates.
Miyakawa N, Nagai Y, Hori Y, Mimura K, Orihara A, Oyama K, Matsuo T, Inoue KI, Suzuki T, Hirabayashi T, Suhara T, Takada M, Higuchi M, Kawasaki K, Minamimoto T. Miyakawa N, et al. Among authors: hirabayashi t. Nat Commun. 2023 Feb 28;14(1):971. doi: 10.1038/s41467-023-36642-6. Nat Commun. 2023. PMID: 36854724 Free PMC article.
355 results