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IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation.
Petersone L, Wang CJ, Edner NM, Fabri A, Nikou SA, Hinze C, Ross EM, Ntavli E, Elfaki Y, Heuts F, Ovcinnikovs V, Rueda Gonzalez A, Houghton LP, Li HM, Zhang Y, Toellner KM, Walker LSK. Petersone L, et al. Among authors: hinze c. J Exp Med. 2023 Oct 2;220(10):e20221653. doi: 10.1084/jem.20221653. Epub 2023 Jul 19. J Exp Med. 2023. PMID: 37466652 Free PMC article.
Therapeutic gene editing of T cells to correct CTLA-4 insufficiency.
Fox TA, Houghton BC, Petersone L, Waters E, Edner NM, McKenna A, Preham O, Hinze C, Williams C, de Albuquerque AS, Kennedy A, Pesenacker AM, Genovese P, Walker LSK, Burns SO, Sansom DM, Booth C, Morris EC. Fox TA, et al. Among authors: hinze c. Sci Transl Med. 2022 Oct 26;14(668):eabn5811. doi: 10.1126/scitranslmed.abn5811. Epub 2022 Oct 26. Sci Transl Med. 2022. PMID: 36288278
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.
Kennedy A, Waters E, Rowshanravan B, Hinze C, Williams C, Janman D, Fox TA, Booth C, Pesenacker AM, Halliday N, Soskic B, Kaur S, Qureshi OS, Morris EC, Ikemizu S, Paluch C, Huo J, Davis SJ, Boucrot E, Walker LSK, Sansom DM. Kennedy A, et al. Among authors: hinze c. Nat Immunol. 2022 Sep;23(9):1365-1378. doi: 10.1038/s41590-022-01289-w. Epub 2022 Aug 23. Nat Immunol. 2022. PMID: 35999394 Free PMC article.
Regulation of CTLA-4 recycling by LRBA and Rab11.
Janman D, Hinze C, Kennedy A, Halliday N, Waters E, Williams C, Rowshanravan B, Hou TZ, Minogue S, Qureshi OS, Sansom DM. Janman D, et al. Among authors: hinze c. Immunology. 2021 Sep;164(1):106-119. doi: 10.1111/imm.13343. Epub 2021 Jun 6. Immunology. 2021. PMID: 33960403 Free PMC article.
Proteomic mapping identifies serum marker signatures associated with MIS-C specific hyperinflammation and cardiovascular manifestation.
Reiter A, Verweyen EL, Queste E, Fuehner S, Jakob A, Masjosthusmann K, Hinze C, Wittkowski H, Foell D, Meinzer U, Melki I, Kessel C; MIS-C Robert-Debré consortium. Reiter A, et al. Among authors: hinze c. Clin Immunol. 2024 May 7:110237. doi: 10.1016/j.clim.2024.110237. Online ahead of print. Clin Immunol. 2024. PMID: 38723855 Free article.
123 results