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ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
Liles JT, Corkey BK, Notte GT, Budas GR, Lansdon EB, Hinojosa-Kirschenbaum F, Badal SS, Lee M, Schultz BE, Wise S, Pendem S, Graupe M, Castonguay L, Koch KA, Wong MH, Papalia GA, French DM, Sullivan T, Huntzicker EG, Ma FY, Nikolic-Paterson DJ, Altuhaifi T, Yang H, Fogo AB, Breckenridge DG. Liles JT, et al. Among authors: hinojosa kirschenbaum f. J Clin Invest. 2018 Oct 1;128(10):4485-4500. doi: 10.1172/JCI99768. Epub 2018 Jul 19. J Clin Invest. 2018. PMID: 30024858 Free PMC article.
ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension.
Budas GR, Boehm M, Kojonazarov B, Viswanathan G, Tian X, Veeroju S, Novoyatleva T, Grimminger F, Hinojosa-Kirschenbaum F, Ghofrani HA, Weissmann N, Seeger W, Liles JT, Schermuly RT. Budas GR, et al. Among authors: hinojosa kirschenbaum f. Am J Respir Crit Care Med. 2018 Feb 1;197(3):373-385. doi: 10.1164/rccm.201703-0502OC. Am J Respir Crit Care Med. 2018. PMID: 28910144
Thioredoxin-2 inhibits mitochondrial reactive oxygen species generation and apoptosis stress kinase-1 activity to maintain cardiac function.
Huang Q, Zhou HJ, Zhang H, Huang Y, Hinojosa-Kirschenbaum F, Fan P, Yao L, Belardinelli L, Tellides G, Giordano FJ, Budas GR, Min W. Huang Q, et al. Among authors: hinojosa kirschenbaum f. Circulation. 2015 Mar 24;131(12):1082-97. doi: 10.1161/CIRCULATIONAHA.114.012725. Epub 2015 Jan 27. Circulation. 2015. PMID: 25628390 Free PMC article.
Intracellular effects of the Hepatitis C virus nucleoside polymerase inhibitor RO5855 (Mericitabine Parent) and Ribavirin in combination.
Ma H, Le Pogam S, Fletcher S, Hinojosa-Kirschenbaum F, Javanbakht H, Yan JM, Jiang WR, Inocencio N, Klumpp K, Nájera I. Ma H, et al. Among authors: hinojosa kirschenbaum f. Antimicrob Agents Chemother. 2014 May;58(5):2614-25. doi: 10.1128/AAC.02250-13. Epub 2014 Feb 18. Antimicrob Agents Chemother. 2014. PMID: 24550342 Free PMC article.