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Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss.
Cell Rep Med. 2022 Nov 15;3(11):100810. doi: 10.1016/j.xcrm.2022.100810.
Cell Rep Med. 2022.
PMID: 36384093
Free PMC article.
A glucagon analogue decreases body weight in mice via signalling in the liver.
Hinds CE, Owen BM, Hope DCD, Pickford P, Jones B, Tan TM, Minnion JS, Bloom SR.
Hinds CE, et al.
Sci Rep. 2021 Nov 19;11(1):22577. doi: 10.1038/s41598-021-01912-0.
Sci Rep. 2021.
PMID: 34799628
Free PMC article.
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Abolishing β-arrestin recruitment is necessary for the full metabolic benefits of G protein-biased glucagon-like peptide-1 receptor agonists.
Hinds CE, Peace E, Chen S, Davies I, El Eid L, Tomas A, Tan T, Minnion J, Jones B, Bloom SR.
Hinds CE, et al.
Diabetes Obes Metab. 2024 Jan;26(1):65-77. doi: 10.1111/dom.15288. Epub 2023 Oct 5.
Diabetes Obes Metab. 2024.
PMID: 37795639
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