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Targeting ubiquilin-1 in Alzheimer's disease.
Takalo M, Haapasalo A, Natunen T, Viswanathan J, Kurkinen KM, Tanzi RE, Soininen H, Hiltunen M. Takalo M, et al. Among authors: hiltunen m. Expert Opin Ther Targets. 2013 Jul;17(7):795-810. doi: 10.1517/14728222.2013.791284. Epub 2013 Apr 21. Expert Opin Ther Targets. 2013. PMID: 23600477 Review.
Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease.
Natunen T, Parrado AR, Helisalmi S, Pursiheimo JP, Sarajärvi T, Mäkinen P, Kurkinen KM, Mullin K, Alafuzoff I, Haapasalo A, Bertram L, Soininen H, Tanzi RE, Hiltunen M. Natunen T, et al. Among authors: hiltunen m. J Alzheimers Dis. 2013;37(1):217-32. doi: 10.3233/JAD-130104. J Alzheimers Dis. 2013. PMID: 23970038
Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease.
Natunen T, Martiskainen H, Sarajärvi T, Helisalmi S, Pursiheimo JP, Viswanathan J, Laitinen M, Mäkinen P, Kauppinen T, Rauramaa T, Leinonen V, Alafuzoff I, Haapasalo A, Soininen H, Hiltunen M. Natunen T, et al. Among authors: hiltunen m. PLoS One. 2013 Nov 20;8(11):e80700. doi: 10.1371/journal.pone.0080700. eCollection 2013. PLoS One. 2013. PMID: 24278306 Free PMC article.
Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach.
Martiskainen H, Helisalmi S, Viswanathan J, Kurki M, Hall A, Herukka SK, Sarajärvi T, Natunen T, Kurkinen KM, Huovinen J, Mäkinen P, Laitinen M, Koivisto AM, Mattila KM, Lehtimäki T, Remes AM, Leinonen V, Haapasalo A, Soininen H, Hiltunen M. Martiskainen H, et al. Among authors: hiltunen m. J Alzheimers Dis. 2015;43(2):565-73. doi: 10.3233/JAD-140777. J Alzheimers Dis. 2015. PMID: 25096612
Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, Huttunen HJ, Hiltunen M. Martiskainen H, et al. Among authors: hiltunen m. Neurobiol Aging. 2015 Feb;36(2):1221.e15-28. doi: 10.1016/j.neurobiolaging.2014.09.003. Epub 2014 Sep 6. Neurobiol Aging. 2015. PMID: 25281018
389 results