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Atomic-scale interactions between quorum sensing autoinducer molecules and the mucoid P. aeruginosa exopolysaccharide matrix.
Sci Rep. 2022 May 11;12(1):7724. doi: 10.1038/s41598-022-11499-9.
Sci Rep. 2022.
PMID: 35545629
Free PMC article.
Cation complexation by mucoid Pseudomonas aeruginosa extracellular polysaccharide.
Hills OJ, Smith J, Scott AJ, Devine DA, Chappell HF.
Hills OJ, et al.
PLoS One. 2021 Sep 2;16(9):e0257026. doi: 10.1371/journal.pone.0257026. eCollection 2021.
PLoS One. 2021.
PMID: 34473773
Free PMC article.
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Polyguluronate simulations shed light onto the therapeutic action of OligoG CF-5/20.
Hills OJ, Yong CW, Scott AJ, Smith J, Chappell HF.
Hills OJ, et al.
Bioorg Med Chem. 2022 Oct 15;72:116945. doi: 10.1016/j.bmc.2022.116945. Epub 2022 Jul 26.
Bioorg Med Chem. 2022.
PMID: 36037625
Free article.
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A DFT study of the gallium ion-binding capacity of mature Pseudomonas aeruginosa biofilm extracellular polysaccharide.
Hills OJ, Poskrobko Z, Scott AJ, Smith J, Chappell HF.
Hills OJ, et al.
PLoS One. 2023 Jun 14;18(6):e0287191. doi: 10.1371/journal.pone.0287191. eCollection 2023.
PLoS One. 2023.
PMID: 37315081
Free PMC article.
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Atomistic modelling and NMR studies reveal that gallium can target the ferric PQS uptake system in P. aeruginosa biofilms.
Hills OJ, Noble IOK, Heyam A, Scott AJ, Smith J, Chappell HF.
Hills OJ, et al.
Microbiology (Reading). 2023 Dec;169(12):001422. doi: 10.1099/mic.0.001422.
Microbiology (Reading). 2023.
PMID: 38117289
Free PMC article.
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