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An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells.
Nat Commun. 2020 May 22;11(1):2584. doi: 10.1038/s41467-020-16327-0.
Nat Commun. 2020.
PMID: 32444635
Free PMC article.
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction.
Colli ML, Hill JLE, Marroquí L, Chaffey J, Dos Santos RS, Leete P, Coomans de Brachène A, Paula FMM, Op de Beeck A, Castela A, Marselli L, Krogvold L, Dahl-Jorgensen K, Marchetti P, Morgan NG, Richardson SJ, Eizirik DL.
Colli ML, et al. Among authors: hill jle.
EBioMedicine. 2018 Oct;36:367-375. doi: 10.1016/j.ebiom.2018.09.040. Epub 2018 Sep 27.
EBioMedicine. 2018.
PMID: 30269996
Free PMC article.
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Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection.
Chaffey JR, Young J, Leslie KA, Partridge K, Akhbari P, Dhayal S, Hill JL, Wedgwood KCA, Burnett E, Russell MA, Richardson SJ, Morgan NG.
Chaffey JR, et al.
Sci Rep. 2021 Aug 2;11(1):15624. doi: 10.1038/s41598-021-94878-y.
Sci Rep. 2021.
PMID: 34341375
Free PMC article.
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Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expression and a Lower β-Cell Mass.
King R, Hill JL, Saha B, Tong Y, Strutt BJ, Russell MA, Morgan NG, Richardson SJ, Hill DJ.
King R, et al.
Nutrients. 2019 Mar 12;11(3):605. doi: 10.3390/nu11030605.
Nutrients. 2019.
PMID: 30871106
Free PMC article.
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Ontology of the apelinergic system in mouse pancreas during pregnancy and relationship with β-cell mass.
Strutt B, Szlapinski S, Gnaneswaran T, Donegan S, Hill J, Bennett J, Hill DJ.
Strutt B, et al.
Sci Rep. 2021 Jul 29;11(1):15475. doi: 10.1038/s41598-021-94725-0.
Sci Rep. 2021.
PMID: 34326390
Free PMC article.
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