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Thymidine Kinase-Independent Click Chemistry DNADetect Probes for DNA Proliferation Assessment in Malaria Parasites.
ACS Chem Biol. 2023 Dec 15;18(12):2535-2543. doi: 10.1021/acschembio.3c00530. Epub 2023 Dec 5.
ACS Chem Biol. 2023.
PMID: 38050717
Labeling of Cellular DNA with a Cyclosal Phosphotriester Pronucleotide Analog of 5-ethynyl-2'-deoxyuridine.
Huynh N, Dickson C, Zencak D, Hilko DH, Mackay-Sim A, Poulsen SA.
Huynh N, et al. Among authors: hilko dh.
Chem Biol Drug Des. 2015 Oct;86(4):400-9. doi: 10.1111/cbdd.12506. Epub 2015 Jan 31.
Chem Biol Drug Des. 2015.
PMID: 25557046
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Development of ethynyl-2'-deoxyuridine chemical probes for cell proliferation.
Lovitt CJ, Hilko DH, Avery VM, Poulsen SA.
Lovitt CJ, et al. Among authors: hilko dh.
Bioorg Med Chem. 2016 Sep 15;24(18):4272-4280. doi: 10.1016/j.bmc.2016.07.021. Epub 2016 Jul 12.
Bioorg Med Chem. 2016.
PMID: 27460697
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Synthesis of 5-Alkynyl Substituted 2'-Arabinosyl 2'-Halogenated Uridine Nucleosides.
Hilko DH, Bornaghi LF, Poulsen SA.
Hilko DH, et al.
Curr Protoc Nucleic Acid Chem. 2019 Jun;77(1):e86. doi: 10.1002/cpnc.86. Epub 2019 May 24.
Curr Protoc Nucleic Acid Chem. 2019.
PMID: 31125509
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Investigation of pyrimidine nucleoside analogues as chemical probes to assess compound effects on the proliferation of Trypanosoma cruzi intracellular parasites.
Sykes ML, Hilko DH, Kung LI, Poulsen SA, Avery VM.
Sykes ML, et al. Among authors: hilko dh.
PLoS Negl Trop Dis. 2020 Mar 12;14(3):e0008068. doi: 10.1371/journal.pntd.0008068. eCollection 2020 Mar.
PLoS Negl Trop Dis. 2020.
PMID: 32163414
Free PMC article.
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Stereoselective Synthesis of Highly Functionalized Arabinosyl Nucleosides through Application of an N-Nitro Protecting Group.
Hilko DH, Bornaghi LF, Poulsen SA.
Hilko DH, et al.
J Org Chem. 2018 Oct 5;83(19):11944-11955. doi: 10.1021/acs.joc.8b01834. Epub 2018 Sep 6.
J Org Chem. 2018.
PMID: 30153729
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Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA.
Petit GA, Mohanty B, McMahon RM, Nebl S, Hilko DH, Wilde KL, Scanlon MJ, Martin JL, Halili MA.
Petit GA, et al. Among authors: hilko dh.
Acta Crystallogr D Struct Biol. 2022 Jan 1;78(Pt 1):75-90. doi: 10.1107/S2059798321011475. Epub 2022 Jan 1.
Acta Crystallogr D Struct Biol. 2022.
PMID: 34981764
Free PMC article.
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